July 2018 in “Elsevier eBooks” Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.
July 2015 in “Cambridge University Press eBooks” The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
May 1994 in “Reactions Weekly” Many medications can cause hair loss or excessive hair growth, which is usually reversible after stopping the drug.
883 citations
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August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
222 citations
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January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
130 citations
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April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
109 citations
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September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
88 citations
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May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
60 citations
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December 2003 in “Journal of Investigative Dermatology” K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.
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November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
32 citations
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August 1999 in “Journal of Investigative Dermatology” Early onset hair loss linked to genetics and androgen levels.
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September 2018 in “Colloids and Surfaces B: Biointerfaces” A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
22 citations
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March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
21 citations
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August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
19 citations
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September 2011 in “Journal of Dermatological Science” TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
17 citations
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July 2018 in “Environmental and Experimental Botany” Silencing NtNCED3-2 gene in tobacco reduces drought tolerance and impairs growth.
13 citations
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January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
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April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
2 citations
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August 2016 in “Experimental Dermatology” Finasteride treats baldness but may cause lasting sexual side effects.
1 citations
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November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
January 2025 in “Human Reproduction Open” 25% of premenopausal women with Type 1 diabetes have undiagnosed androgen excess disorders.
The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.
January 2025 in “Annals of Dermatology” New treatments for hair loss include low-dose oral minoxidil, light therapy, and innovative therapies targeting hair growth mechanisms.
Taking too much biotin can mess up blood test results, which might lead to wrong diagnoses and treatments.
April 2018 in “Journal of Investigative Dermatology” Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
80 citations
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June 2002 in “Molecular Biology of the Cell” Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
69 citations
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November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.