research The hair growth promoting effect of extract and its molecular regulation
Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
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research The hair growth promoting effect of Sophora flavescens extract and its molecular regulation
Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Hair loss in women with hyperandrogenism: Four cases responding to finasteride
Finasteride improves hair loss in women with hyperandrogenism.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Medical management of male pattern hair loss
Minoxidil and finasteride can slow or halt hair loss, but may have side effects.
research Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research The potential of androgenic alopecia management from plant derivatives
Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
research Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss
Black raspberry extract may help with hair growth, skin whitening, and weight loss.
research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells
Garden cress extract may help treat skin inflammation and androgen-related disorders.
research Serenoa repens and N‐acetyl glucosamine/milk proteins complex differentially affect the paracrine communication between endothelial and follicle dermal papilla cells
Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
research Phytochemistry and pharmacological studies of Plumbago zeylanica L.: a medicinal plant review
Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.
research Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay
A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
research Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens
Some herbs show promise as antiandrogenic agents.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Androgenetic alopecia; drug safety and therapeutic strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression
Bee venom helps hair grow and may work better than some common treatments.
research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research Finasteride-induced depression: new insights into possible pathomechanisms
Finasteride may increase depression by reducing brain cell growth.
research Terminalia chebula retz. Fruit Extract Promotes Murine Hair Growth by Suppressing 5α-Reductase and Accelerating the Degradation of Dihydrotestosterone
Terminalia chebula fruit extract helps hair growth by reducing DHT and boosting hair cell activity.
research Mechanism of action of herbs and their active constituents used in hair loss treatment
Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
research Causes of hair loss and the developments in hair rejuvenation
Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.
research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men
Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
research 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid
Rice bran extract might help prevent hair loss.
research Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride
Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
research Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Association Between 5-Alpha Reductase Inhibitor Use and The Risk of Depression: A Meta-Analysis.
Using 5-alpha reductase inhibitors may increase the risk of mild depression.
research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.