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Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.

Finasteride reduces movement issues in Parkinson's disease rats.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Finasteride safely lowers DHT levels without affecting testosterone.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Some dibenzo compounds might help treat cancer with fewer side effects.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Both drugs lower DHT levels, with GI198745 being more effective.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

New compounds may soon be tested to treat excessive hair growth in women.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.