139 citations
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February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Transplant success has improved with better immunosuppressive drugs and donor matching.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
127 citations
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March 2016 in “PLoS ONE” Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.
117 citations
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November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
114 citations
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January 2007 in “Drug Safety” Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
114 citations
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December 1951 in “Archives of Dermatology” Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.
113 citations
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March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
105 citations
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August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
86 citations
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July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
86 citations
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January 2008 in “Journal of nutritional & environmental medicine” Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
85 citations
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July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
82 citations
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September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
77 citations
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June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
77 citations
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June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
75 citations
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January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
75 citations
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June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
73 citations
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July 2016 in “Cosmetics” Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
71 citations
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September 2007 in “Cancer” Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
71 citations
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May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
70 citations
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October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
69 citations
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November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
66 citations
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January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
66 citations
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April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
60 citations
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May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
59 citations
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June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
59 citations
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November 2015 in “International Journal of Cosmetic Science” Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
55 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
54 citations
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August 2017 in “Gynecological Endocrinology” Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
54 citations
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July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.