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A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.

The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.

Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.

CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.

Targeting PTEN can improve healing in venous leg ulcers.

Anti-Ku-positive patients often have muscle weakness and autophagy plays a key role in their condition.

Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

A gene mutation in mice causes skin defects and early death.

UVA exposure worsens hair loss by activating a specific cell pathway.

The mTOR signaling pathway might play a role in radiation dermatitis, but more research is needed.

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

OXI1 kinase is essential for plant defense and root hair growth in Arabidopsis.

The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.

Mcl-1 can activate Wnt signaling in skin cells, promoting growth and possibly cancer.

Grasp protein helps maintain skin health after UVB exposure.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Microsporum gypseum fungus breaks down keratin in hair by digesting it enzymatically, starting with less keratinized parts.

Cathepsin L is essential for normal hair growth and development.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.