14 citations
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May 2021 in “Marine Drugs” PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
September 2007 in “The American Journal of Gastroenterology” Recognizing lupus as a cause of severe gut issues is crucial for effective treatment.
38 citations
,
November 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
33 citations
,
June 2012 in “Journal of Crohn's and colitis” Alopecia Areata might be linked to Crohn's disease.
2 citations
,
February 2014 in “Journal of Crohn's and colitis” Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.
May 2011 in “British Journal of Dermatology” The 1891 epidemic skin disease was likely caused by arsenic poisoning, possibly from beer or fish.
84 citations
,
August 2023 in “Drugs” Ritlecitinib is approved in the USA and Japan for treating severe hair loss in people aged 12 and older.
18 citations
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March 1984 in “BMJ” Minoxidil helps hair regrowth in alopecia, but more research needed.
12 citations
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January 1984 in “Anesthesia & Analgesia” Anesthesia and surgery can cause temporary hair loss, but hair usually grows back without treatment.
5 citations
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September 2011 in “Pediatric Dermatology” Two young siblings experienced hair loss without hormone issues or other skin problems.
3 citations
,
June 1989 in “Diseases of the Colon & Rectum” Some patients temporarily lost hair after a certain bowel surgery, but it grew back without needing special treatment.
1 citations
,
January 2013 in “The Journal of Dermatology” A skin condition called pyodermatitis vegetans was found in a patient with multiple myeloma for the first time.
118 citations
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July 2005 in “Journal of Ethnopharmacology” Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.
73 citations
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May 1976 in “JAMA” Long-term parenteral nutrition without zinc can cause severe zinc deficiency.
60 citations
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September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
44 citations
,
September 2014 in “Cell Death & Differentiation” Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
27 citations
,
September 2015 in “PharmaNutrition” Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
26 citations
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August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
19 citations
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September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
18 citations
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April 2013 in “Inflammatory Bowel Diseases” People with Inflammatory Bowel Disease often lose hair due to stress, medication side effects, or lack of nutrients, and treatment depends on the specific cause.
14 citations
,
January 2020 in “Advances in Dermatology and Allergology” Higher interleukin-15 levels are linked to more severe alopecia areata, but not to age or gender.
14 citations
,
August 2018 in “Nanoscale Research Letters” Turmeric may improve knee osteoarthritis, depression, and metabolic syndrome, but evidence is weak.
14 citations
,
August 2006 in “Clinical and Experimental Dermatology” A girl with no hair neglect developed plica neuropathica in the hospital, lost all her hair, but it grew back.
13 citations
,
June 2010 in “Journal of The American Academy of Dermatology” A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
11 citations
,
November 2021 in “BMJ Open” People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
11 citations
,
February 2021 in “Journal of Cosmetic Dermatology” Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.
5 citations
,
December 2012 in “Journal of Dermatology” Wigs greatly improve life quality for hair loss patients.
3 citations
,
August 2024 in “Cureus” Upadacitinib may cause hair loss.
3 citations
,
August 2020 in “Case Reports in Dermatology” Tofacitinib treatment significantly improved a patient's psoriasis, psoriatic arthritis, and alopecia universalis.
2 citations
,
March 2015 in “Toxicology and Environmental Health Sciences” Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.