research 120 Identification of post-translationally modified trichohyalin epitopes responsible for triggering autoimmunity in alopecia areata
Trichohyalin in hair can trigger immune attacks in alopecia areata.
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research Ultrastructural Localization of Hair Keratins in Human Scalp Hair Shafts as Revealed by Rapid-Freezing Immunocytochemistry.
Hair keratins are mainly on macrofibrils in the cortex and in the endocuticle in the cuticle.
research The Role of Gold - Silver Nanocomposite Gel versus Astragalus Polysaccharides on Healing Process of Experimentally Induced Wound in Albino Rats Pharmacological and Histological Comparative Study
Astragalus polysaccharides nanogel heals wounds better than Gold-Silver nanocomposite gel.
research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Biocompatibility of KAPs-Depleted Residual Hair
KAP-depleted hair causes less immune response and is more biocompatible for implants.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization
The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
research Establishment of a culture model for the prolonged maintenance of chicken feather follicles structure in vitro
Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research The effects of narrowbands of visible light upon some skin disorders: a review
Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
research New insights into human hair: SAXS, SEM, TEM and EDX for Alopecia Areata investigations
Alopecia Areata causes significant structural and compositional changes in hair.
research The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal–Epidermal Junction of Mouse Skin
Certain skin proteins can form anchoring structures without the protein AMACO.
research Focused Review on Metal Nanoparticles in Hair Regeneration and Alopecia: Insights into Mechanisms, Assessment Techniques, Toxicity, Regulatory and Intellectual Property Perspectives
Metal nanoparticles show promise for treating hair loss but need more research to ensure safety.
research Nanotechnology Approaches in Chronic Wound Healing
Nanotechnology shows promise for better chronic wound healing but needs more research.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Green Nanodrugs: Research Progress and Challenges of Plant-Derived Nanovesicles in Tumor Treatment
Plant-derived nanovesicles show promise in cancer treatment but need standardized preparation.
research Challenges in the Physical Characterization of Lipid Nanoparticles
Characterizing lipid nanoparticles is challenging due to issues with sensitivity, reproducibility, and reliability.
research UNCONVENTIONAL PROTEIN SECRETION OF KERATIN 75 BY AMELOBLASTS IN VIVO
Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.
research Enhanced remyelination during late pregnancy: involvement of the GABAergic system
Late pregnancy helps repair brain damage in rats due to the GABAergic system.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.
research Human hair follicle organ culture: theory, application and perspectives
Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
research Histopathology of alopecia: a clinicopathological approach to diagnosis
The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
research Dissecting hair breakage in alopecia areata: the central role of dysregulated cysteine homeostasis
Disrupted cysteine metabolism may cause hair breakage in Alopecia Areata, suggesting potential treatments like N-acetylcysteine.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.
research Rational Design and Functionalization of Melt Electrowritten 4D Scaffolds for Biomedical Applications
4D scaffolds made with melt electrowriting can change shape for use in medicine.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Expression and roles of steroidogenic acute regulatory (StAR) protein in ‘non-classical’, extra-adrenal and extra-gonadal cells and tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute
Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.