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Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

Early diagnosis of PSIS can lead to normal height with growth hormone and testosterone treatment.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Some skin diseases and their treatments can negatively affect male fertility.

People in Jeddah know about Vitamin D and its sources but are unclear on how much they need daily, and while many women take supplements, attitudes towards increasing Vitamin D levels vary.

A rare benign skin nodule was found on the buttock, a unique location for this condition.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.

A new mouse mutation causes skin and hair defects due to a gene change.

Congenital atrichia with papular lesions causes permanent hair loss and skin bumps due to a gene mutation.

Immature blackbuck pancreas has underdeveloped goblet cells and similar Langerhans islets in both sexes.

Extracellular vesicles from amniotic fluid stem cells can improve underdeveloped fetal lungs.

The conclusion is that the variation in hair thinness in patients is mostly due to the amount of underdeveloped hairs, and treatments that thicken fine hairs might work for those with mild to severe conditions.

A rare fetal malformation caused difficult birth in a goat, requiring surgery.

Iron supplements improve life quality for people with anemia.

Bovines can have rare inherited skin diseases with specific symptoms like hair loss, fragile skin, and abnormal porphyrin buildup.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Overexpression of the glucocorticoid receptor in mice causes developmental defects similar to ectodermal dysplasia.

Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.

Iodine deficiency in lambs causes poor growth, less wool, and delayed sexual maturity.

The type 3 IP3 receptor is important for controlling hair loss and growth.