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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Over 40% of women have unwanted facial hair, which can affect their self-image, and should be managed with personalized treatment and support.

Many transgender men on testosterone therapy experience hair loss.

Hormones beyond androgens may cause acne and hair loss.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Modern beauty standards encourage women to remove pubic hair for aesthetic and social reasons.

People often underestimate hair loss severity, with fewer seeking treatment, and it's more distressing for women.

Finasteride can cause enlarged breasts.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

A female dog with mixed male and female traits was treated successfully with surgery.

Gender-affirming hormone therapy may increase heart disease risk in transgender individuals.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.

A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Delayed puberty often runs in families, can affect growth, and may need hormone treatment.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.

Androgen levels do not determine the type of PCOS symptoms in young females.

Omega-6 fats in certain cells boost male hormone production.

Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.

A woman with non-classic CAH had unusual heavy periods and high hormone levels, improved with treatment.

Hyperandrogenism does not affect young women's sexual function.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.