February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
10 citations
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November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
June 2025 in “British Journal of Dermatology” Segmented hair color changes can indicate active alopecia areata.
March 2013 in “Pigment Cell & Melanoma Research” A gene called Taqpep affects cat coat patterns like stripes and blotches.
2 citations
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September 2020 in “International journal of radiology & radiation therapy” Radiotherapy can cause rare changes in hair color, which should be discussed with patients.
May 2021 in “GSC Advanced Research and Reviews” Hair color is influenced by genetics and can indicate certain health conditions.
15 citations
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June 1993 in “Archives of Dermatology” A 22-year-old's gray hair partially turned back to its original color without known causes.
4 citations
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March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
Skin diseases look different on pigmented and nonpigmented skin.
January 2026 in “Deutsches Ärzteblatt international”
39 citations
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August 2005 in “Dermatologic surgery” Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.
4 citations
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September 2017 in “Dermatologic surgery” The combination therapy improved skin pigmentation.
Immunological skin diseases in pigs are rare and can be caused by immune system issues or external factors.
October 2024 in “Skin Research and Technology” Pili annulati causes zebra-striped hair but doesn't affect hair strength or quality of life.
12 citations
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January 2021 in “Dermatology Research and Practice” The 1927 nm Thulium laser effectively and safely treats postinflammatory hyperpigmentation in darker skin tones.
December 2024 in “Annals of Medicine and Surgery” Early diagnosis of pseudopelade of Brocq in men is crucial to prevent permanent hair loss.
8 citations
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May 2012 in “Clinical and Experimental Dermatology” An 82-year-old woman's hair turned white suddenly, likely due to a rare form of alopecia that targets pigmented hair.
74 citations
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July 1995 in “PubMed” Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.
9 citations
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July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
1 citations
,
January 2009 A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.
4 citations
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July 2021 in “Skin Appendage Disorders” Sudden hair whitening may be linked to immune system activity.
14 citations
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September 2017 in “General and comparative endocrinology” Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
June 2025 in “British Journal of Dermatology” A rare skin condition in a boy is likely due to a specific genetic mutation pattern.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
2 citations
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June 2020 in “Dermatology and therapy” Narrowband-UVB phototherapy successfully treated a rare case of Graham Little-Piccardi-Lassueur syndrome.
Acitretin treatment unexpectedly darkened a patient's gray hair.
August 2019 in “Anais Brasileiros de Dermatologia”
February 2009 in “Springer eBooks” Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
September 2023 in “Journal of the American Academy of Dermatology” Spanish speakers with limited English search most for "pigmentation/dark spots."
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Ectopic acanthosis nigricans can occur at surgical sites due to skin graft mismatches.