research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
Search
for
Sort by
Research
390-420 / 1000+ results research Spectrophotometric and Stability Indicating RP-HPLC-PDA method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Tablet Dosage form
The methods accurately measure Finasteride and Tamsulosin in tablets.
research Mitogen‐regulated protein/proliferin mRNA induction following single applications of tumor promoters to murine skin
mrp/plf-mRNA can indicate tumor-promoting effects in skin.
research Protoporphyrin IX: the Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
A patient with total hair loss developed vitiligo after using a treatment called DCP.
research An overview of unwanted female hair
Over 40% of women have unwanted facial hair, which can affect their self-image, and should be managed with personalized treatment and support.
research Modulation of T Cell Responses by Fucoidan to Inhibit Osteogenesis
Fucoidan reduces bone cell formation by affecting T-cell activity.
research Association of frontal fibrosing alopecia and contact allergens in everyday skincare products in Hispanic females: a case-control study
Increased sunscreen use may be linked to frontal fibrosing alopecia in Hispanic females.
research Concomitant management of alopecia universalis and ulcerative colitis with upadacitinib
Upadacitinib helped regrow hair and maintain ulcerative colitis remission.
research Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia
Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis
Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.
research 054 Post Finasteride Syndrome: Guess Who-Demographics from FDA Database
Younger people (median age 35) experience more PFS-like symptoms with 1mg finasteride; more research needed.
research Decision letter: Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
research Reversible visual loss caused by combination therapy of alfuzosin and finasteride in a patient with uveitic glaucoma
Taking alfuzosin and finasteride together caused temporary vision loss in a glaucoma patient, but switching to tamsulosin helped.
research Use of Leukocyte Platelet (L-PRF) Rich Fibrin in Diabetic Foot Ulcer with Osteomyelitis (Three Clinical Cases Report)
L-PRF treatment helped heal diabetic foot ulcers effectively.
research ISHRS: Expanding FUE Education
The document's conclusion cannot be provided as the content is not available to parse.
research Challenges to PrEP use and perceptions of urine tenofovir adherence monitoring reported by individuals on PrEP
Remembering to take PrEP is the main challenge, and urine monitoring is a preferred adherence method.
research An observational analysis of erythromelanosis follicularis faciei et colli
EFFC might be common but underreported.
research PEGylated Flavonoid Aspasomes as a Brain-Targeted Nano-Vesicular Platform for Enhanced Neuroprotection in Stress-Induced Cognitive Dysfunction
The study investigates PEGylated flavonoid Aspasomes as a brain-targeted nano-vesicular platform for neuroprotection in stress-induced cognitive dysfunction. The optimized formulation (F14) demonstrated high entrapment efficiency, nanosized vesicles, and enhanced drug release and nasal permeation compared to free luteolin (LUT). In chronic unpredictable stress rats, F14 significantly improved spatial memory and reduced depressive-like behavior more effectively than free LUT. Biochemical analysis showed superior reductions in hippocampal acetylcholinesterase activity and serum corticosterone, along with increased brain-derived neurotrophic factor levels. Histopathological examination confirmed preserved hippocampal architecture in treated rats. These findings suggest that PEGylated LUT-Aspasomes enhance stability, brain delivery, and neuroprotective efficacy, offering a promising approach for managing stress-related neurobehavioral disorders.
research Suicidal behaviors (suicidal ideation, suicide attempt and completed suicide) in patients treated with finasteride for hair loss: Results from the U.S. FDA Adverse Event Reporting System (FAERS) database
research CORRECTION: Revision of Published FUE Terminology Definitions
The document corrects the definitions of terms related to FUE, a hair transplant technique.
research Finasteride: a 5 alpha-reductase inhibitor.
research A pilot study of 2% tofacitinib cream with narrowband ultraviolet B for the treatment of facial vitiligo
Using 2% tofacitinib cream with narrowband ultraviolet B improved facial vitiligo by 70% in patients who didn't respond to previous treatments, with no side effects reported.
research Simultaneous Determination of Quercitrin, Afzelin, Amentoflavone, Hinokiflavone in Rat Plasma by UFLC–MS-MS and Its Application to the Pharmacokinetics of Platycladus orientalis Leaves Extract
Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.
research Frontal Fibrosing Alopecia. An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
Excessive sun protection might contribute to frontal fibrosing alopecia.
research Donor hair follicle preservation by partial follicular unit extraction. A method to optimize hair transplantation
Partial hair follicle extraction can effectively double the number of hair follicles for transplants, with most surviving and growing normally after a year.
research T cell–mediated acute localized exanthematous pustulosis caused by finasteride
Finasteride caused a rare skin rash in a man, which improved after stopping the medication.
research Paroxysmal Nocturnal Hemoglobinuria in Systemic Lupus Erythematosus: A Rare Manifestation.
PNH can occur in patients with SLE, so doctors should be aware of this.
research Follicular Unit Extraction
FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.
research UVA-1 in the treatment of alopecia areata
UVA-1 phototherapy might help treat alopecia areata.