265 citations
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July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
232 citations
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
96 citations
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
95 citations
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
59 citations
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February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
55 citations
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March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
46 citations
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
40 citations
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June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
34 citations
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April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
28 citations
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March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
26 citations
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April 1999 in “Dermatologic Clinics” The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.
22 citations
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August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
18 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
17 citations
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March 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
14 citations
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October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
12 citations
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August 2020 in “Frontiers in Genetics” H19 boosts hair growth potential by activating Wnt signaling, possibly helping treat hair loss.
11 citations
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May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
11 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
9 citations
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
7 citations
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January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
6 citations
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November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
6 citations
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September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
5 citations
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May 2020 in “Life science alliance” Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
5 citations
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March 2020 in “Cell and Tissue Banking” Injected cells show potential for hair growth.
5 citations
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March 2019 in “Scientific Reports” The technique can isolate cells to help treat skin pigmentation issues.
5 citations
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October 2018 in “American Journal of Clinical Dermatology” Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.
5 citations
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December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.