3 citations
,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” Platelet-Rich Plasma may improve skin health and reduce wrinkles, but more research is needed for standard treatment guidelines.
April 2017 in “Journal of Investigative Dermatology” Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
36 citations
,
February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
76 citations
,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
1 citations
,
December 1996 in “Journal of Clinical Laser Medicine & Surgery” A doctor describes a new, less expensive method for treating skin issues with a laser, and another doctor corrects a false claim about hair transplantation results.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
12 citations
,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
18 citations
,
May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
1 citations
,
October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
15 citations
,
July 1991 in “International Journal of Dermatology” Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
June 2018 in “Global Journal of Reproductive Medicine” Idiopathic hirsutism may be linked to increased skin enzyme activity, and new treatments like laser and eflornithine cream show promise.
264 citations
,
January 2008 in “Journal of biomedical optics” Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
55 citations
,
June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
1 citations
,
January 2015 in “Journal of Pigmentary Disorders” Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
73 citations
,
April 1999 in “Dermatologic Clinics” Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.
4 citations
,
December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
4 citations
,
September 2012 in “Journal of dermatological science” The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Men are increasingly seeking quick-result cosmetic treatments for their thicker, oilier skin and hair loss issues.
108 citations
,
December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
40 citations
,
January 2018 in “Pharmaceutics” Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
15 citations
,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
6 citations
,
September 2016 in “American journal of medical and biological research” Male cattle skin is better for quality leather production.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.