May 2017 in “Urology and andrology” Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
35 citations
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May 2002 in “Journal of the European Academy of Dermatology and Venereology” Chronic pelvic pain in men is common, but its cause is unknown and treatments are often ineffective.
April 2019 in “Journal of the Endocrine Society” A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
Finasteride treatment increased blood volume and reduced vessel leakiness in beagle prostates.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
1 citations
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January 2023 in “International journal of urology” Low zinc levels are linked to low testosterone but not to sexual problems.
1 citations
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August 2023 in “Andrology” Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
216 citations
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November 1999 in “Fertility and Sterility” Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.
57 citations
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August 1995 in “British Journal of Dermatology” Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
56 citations
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November 2007 in “Molecular and cellular endocrinology” Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
96 citations
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September 1975 in “The Journal of Clinical Endocrinology & Metabolism” Hormone levels change during puberty, leading to physical developments like pubic hair and voice changes.
8 citations
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April 2008 in “The Journal of Urology” BPH management needs better long-term studies and prevention strategies.
6 citations
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May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
October 2015 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” Finasteride reduces prostate size and PSA levels in young men with hair loss.
July 2004 in “Current Urology Reports” 5-ARI therapy may help prevent prostate cancer progression.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with androgenetic alopecia do not have elevated DHEA-S levels.
38 citations
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August 2003 in “International Journal of Urology” Finasteride and levofloxacin effectively reduce chronic bacterial prostatitis severity.
2 citations
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January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
17 citations
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February 2014 in “Pediatric Research” July 2020 in “Vestnik urologii” The cause of post-finasteride syndrome is unclear and needs more research.
April 2020 in “Journal of the Endocrine Society” Early diagnosis of PSIS can lead to normal height with growth hormone and testosterone treatment.
3 citations
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May 1990 in “Journal of Steroid Biochemistry” Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.
6 citations
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March 2015 in “Journal of Endocrinological Investigation” Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
28 citations
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August 2011 in “Journal of The American Academy of Dermatology” Early hair loss may indicate prostate issues.
20 citations
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April 2023 in “The Journal of Urology” PRP is safe but not more effective than a placebo for treating mild to moderate erectile dysfunction.
October 2010 in “Journal of Men's Health” The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
January 2026 in “Food and Nutrition Sciences” USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.
Adherence to finasteride treatment for prostate issues is generally low.
11 citations
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September 1990 in “Clinical Endocrinology” Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.