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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

A functional medicine approach may help long COVID patients by focusing on adrenal fatigue, gut health, and vitamin D deficiency, using diagnostic tools and lifestyle changes.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Hair follicles and urine cell pellets are promising for transcriptome studies.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Hair follicles and urine cell pellets are promising for transcriptome studies due to consistent quality and useful expression profiles.

Finasteride treatment changes certain urine metabolites in male pattern baldness patients.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Certain metabolites may help diagnose and predict polycystic ovary syndrome.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

A fast and accurate method was developed to measure alfuzosin and dutasteride in human plasma.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

A new method accurately measures nine specific hormones in human blood.

A new method was developed to analyze certain hormones and drugs in human blood efficiently.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

A quick method was developed to detect banned substances in urine for doping control.

Finasteride treatment changes hormone levels in male pattern baldness patients.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

Monitoring steroid hormones in blood can better detect testosterone doping.

The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

A quick method effectively detects banned substances in urine.

Ulcerative colitis involves immune activation, chronic inflammation, and metabolic issues, some of which persist even during remission.