January 2024 in “Specialty journal of Pharmacognosy Phytochemistry and Biotechnology” Genetic factors may influence how well valproic acid works and its side effects in epilepsy treatment.
36 citations
,
October 2008 in “European journal of paediatric neurology” Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.
October 2020 in “The American journal of gastroenterology” Para-aminobenzoic acid in hair supplements can cause autoimmune hepatitis.
2 citations
,
September 2015 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi” Valproic acid can very rarely cause nail separation, which usually gets better on its own after stopping the drug.
22 citations
,
September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
16 citations
,
March 1986 in “Biochemical Pharmacology”
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
October 2011 in “The American Journal of Gastroenterology” Esomeprazole can cause hepatitis.
January 2026 in “Open Science Framework” More research is needed to find effective treatments for hair loss caused by valproic acid.
76 citations
,
May 2011 in “Liver transplantation” Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
20 citations
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August 1981 in “Developmental Medicine & Child Neurology” 13 citations
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June 1981 in “Developmental Medicine & Child Neurology” 10 citations
,
November 2019 in “American Journal of Tropical Medicine and Hygiene” Overdosing on veterinary albendazole can cause severe health issues like hair loss and low blood cell count.
14 citations
,
August 2021 in “Molecular Genetics and Metabolism Reports” Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
7 citations
,
September 1999 in “PubMed” Eating grouper fish liver can cause vitamin A poisoning with severe symptoms.
14 citations
,
June 1952 in “The BMJ” Phenobarbitone can cause severe and sometimes fatal skin reactions.
July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Applying valproic acid on the scalp increased hair growth in men with hair loss.
January 2024 in “Arquivos de Neuro-Psiquiatria” Consider THPP in patients with muscle weakness and low potassium, as it is often underdiagnosed.
2 citations
,
August 2004 Early diagnosis and proper treatment improve outcomes for methylmalonic acidemia.
May 2024 in “Endocrine practice” Vitamin A toxicity can cause serious health issues like hypercalcemia and is often overlooked.
1 citations
,
March 2016 in “Neurotoxicity Research” Finasteride may protect brain and improve behavior in rats with liver failure.
Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.
November 2014 in “Clinical Neurophysiology” High doses of progesterone can reduce seizures in mice.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
June 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” Progesterone and its metabolites can prevent seizures without major side effects.
11 citations
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January 2016 in “Molecular and Cellular Neuroscience” Chronic ethanol increases certain brain receptor levels, influenced by steroids and protein changes.
84 citations
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December 2018 in “Genetics in Medicine” Pegvaliase is recommended for treating adults with phenylketonuria.