5 citations
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September 2024 in “International Journal of Molecular Sciences” 3D bioprinted lung cancer models in a mouse-like structure offer a better way to study radiation effects without using live animals.
September 2004 in “Experimental Dermatology” The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
January 2025 in “Online Publication Service of Würzburg University (Würzburg University)” A protocol was developed to create 3D skin models from adult diseased cells to study Small Fiber Neuropathy.
2 citations
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August 2022 in “genesis” Intravital imaging advances help study bone and dental stem cells in real-time, despite technical challenges.
December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.
August 2026 in “Regenerative Biomaterials” This review discusses the limitations of conventional animal models and two-dimensional cultures in studying cutaneous pigmentary disorders such as vitiligo, melasma, post-inflammatory hyperpigmentation, and solar/senile lentigines. It evaluates advanced in vitro models, including ex vivo explants, co-cultures, three-dimensional skin equivalents, bioprinted constructs, organoids, and skin-on-a-chip platforms. These models are assessed based on their ability to replicate human pigmentation processes, disease-specific pathological processes, and their potential for mechanistic studies and therapeutic evaluation. The review highlights challenges such as vascular and immune integration, long-term stability, and regulatory acceptance, emphasizing the need for improved models within the framework of New Approach Methodologies.
3 citations
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June 2025 in “Wound Repair and Regeneration” 3D bioprinting shows promise for creating skin substitutes, but standardized methods are needed for clinical use.
October 2021 in “QJM: An International Journal of Medicine” The experiment successfully created a 3D model of a rat lung using a natural scaffold.
11 citations
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September 2024 in “Journal of Advanced Research” 3D-bioprinting models of pancreatic cancer could help personalize treatments but need more testing.
November 2022 in “Institutional Repositories DataBase (IRDB)” June 2026 in “Disease Models & Mechanisms” In vitro models help us understand diseases and speed up drug development.
July 2024 in “Journal of Investigative Dermatology” Bioengineered skin models aging well, useful for studying aging and testing treatments.
July 2026 in “Frontiers in Bioengineering and Biotechnology” A combination of advanced human-relevant models and new technologies is needed to improve wound healing research.
5 citations
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February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” 3D cell cultures produce extracellular vesicles similar to those in the body.
29 citations
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May 2023 in “Cell” 60 citations
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February 2015 in “Biomaterials” A surface with VEGF can specifically capture endothelial cells from flowing fluids.
25 citations
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April 2021 in “npj Regenerative Medicine” Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
New bio-ink can print complex tissues and organs.
January 2026 in “Cellular and Molecular Bioengineering” A 3D model of Dupuytren’s disease was developed for better drug testing.
8 citations
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December 2017 in “Current Opinion in Cell Biology” 3D bioengineering can potentially regenerate complex oral organs for future therapies.
56 citations
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October 2024 in “Advanced Materials” Bioprinting is advancing towards creating personalized tissues and organs, but challenges remain for clinical use.
221 citations
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June 1999 in “In Vitro Cellular & Developmental Biology - Animal” 
8 citations
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January 2023 in “Journal of Clinical and Translational Hepatology” Advancements in cultured models improve understanding and treatment of gallbladder cancer.
28 citations
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June 2023 in “Small” VVF alone can't fully describe porosity in granular scaffolds.
50 citations
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November 2010 in “Tissue Engineering Part A” Hair follicle cells and intestinal tissue can create strong, functional blood vessel replacements.
2 citations
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January 2024 in “Frontiers in Bioscience-Landmark” Humanized animal models using human stem cells can improve disease research and drug testing.
5 citations
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October 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.
421 citations
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January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.