January 2026 in “Andrology” PRP injections are safe but don't significantly improve Peyronie's Disease.
The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.
2 citations
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January 2016 in “Andrology”
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
35 citations
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May 2002 in “Journal of the European Academy of Dermatology and Venereology” Chronic pelvic pain in men is common, but its cause is unknown and treatments are often ineffective.
May 2017 in “Urology and andrology” Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
9 citations
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April 2007 in “Journal of Andrology” Excessive pre-ejaculation can be treated with certain medications.
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
13 citations
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November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
November 2003 in “PubMed”
Finasteride may increase stroke risk in people with clotting tendencies.
October 2009 in “Nature Reviews Urology” 8 citations
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October 2021 in “The international journal of risk and safety in medicine” The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
Finasteride treatment increased blood volume and reduced vessel leakiness in beagle prostates.
8 citations
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April 2022 in “Urology Practice” Patients should consult urologists for evidence-based erectile dysfunction treatments.
November 2019 in “Nosotchu” Man had stroke possibly linked to hair loss medications finasteride and minoxidil.
December 2021 in “Indian Journal of Dermatology, Venereology and Leprology” Men with androgenetic alopecia, or hair loss, often have abnormal blood flow in their small blood vessels, which might be linked to inflammation and stress.
June 2018 in “Evidence-Based Practice” Finasteride can double the risk of sexual problems like ejaculation issues, low libido, and impotence.
2 citations
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May 2022 in “International Journal of Impotence Research” Finasteride may be linked to Peyronie’s disease, but more research is needed.
34 citations
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December 2021 in “Journal of Clinical Medicine” Men with BPH should discuss potential sexual side effects with doctors before treatment, as some treatments can affect ejaculation.
February 2019 in “Yeni Üroloji Dergisi” Premature hair whitening or loss may indicate a risk for erectile dysfunction.
June 2026 in “Frontiers in Medicine” 5α-reductase inhibitors for hair loss can cause mild, reversible sexual side effects in some men.
October 2021 in “European urology open science” April 2018 in “The Journal of Urology” Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.
April 2018 in “The Journal of Urology” Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.
January 2008 in “Journal of Medicinal Chemistry” Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
October 2025 in “Journal of the Endocrine Society” Finasteride lowers cholesterol but doesn't reduce heart-related events.
January 2017 in “Revista da Universidade Vale do Rio Verde” Finasteride is commonly used for male pattern hair loss but has potential risks, including irreversible sexual dysfunction.
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.