April 2016 in “Journal of Investigative Dermatology” Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
July 2022 in “Journal of Investigative Dermatology” Vitamin D receptor actions without binding are crucial for healthy skin and hair.
April 2018 in “Journal of Investigative Dermatology” NDRG1 protein helps infantile hemangioma, a common infant tumor, to grow, and its mismanagement by FOXO1 protein plays a big role in causing the tumor.
1 citations
,
April 2023 in “Preprints.org” SEFFI is a safe and effective anti-aging treatment with few complications.
15 citations
,
June 2015 in “PLoS ONE” Thymosin beta-4 promotes hair growth in mice.
20 citations
,
July 2017 in “Scientific Reports” A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
5 citations
,
January 2016 in “Elsevier eBooks” Using a specific binding agent and low doses of FK506 can stimulate stem cells, speeding up skin healing by 25% and improving skin quality in rats and mice.
August 2024 in “Life Science Alliance” Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
October 2015 in “Regenerative Medicine” Two growth factors, PDGF and FGF2, can potentially be used together to grow enough cells for a hair loss treatment, but their exact function on human cells needs further confirmation.
26 citations
,
January 2016 in “Annals of Dermatology” Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.
November 2024 in “Journal of Investigative Dermatology” Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
113 citations
,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
62 citations
,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
Higher levels of certain proteins in hair loss areas may help understand and treat hair loss.
4 citations
,
June 1998 in “The Journal of Clinical Endocrinology & Metabolism” KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
December 2020 in “Research Square (Research Square)” A genetic change in the FGF5 gene affects hair growth in cashmere goats.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” The treatments stopped hair regrowth in mice.
44 citations
,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
131 citations
,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
18 citations
,
October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
94 citations
,
March 1996 in “Journal of Investigative Dermatology” 11 citations
,
November 2021 in “JBMR plus” The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
1 citations
,
July 2019 in “Small ruminant research” Nerve growth factor helps cashmere goat hair cells grow by activating a specific protein.
January 2012 in “Journal of Northwest A & F University” The Eda gene helps regulate the hair cycle in goats.
2 citations
,
October 2018 in “Archives of Dermatological Research” Tofacitinib helps mice grow more hair by increasing noggin and BMP4 levels, possibly better than minoxidil.
March 2024 in “Plant physiology” GLABRA 2 controls ethylene production to help root hair growth during nutrient deficiency.
21 citations
,
September 2019 in “International Journal of Nanomedicine” RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.