research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
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60-90 / 1000+ resultsresearch When whorls collide: the development of hair patterns in frizzled 6 mutant mice
Hair follicles in mutant mice self-organize into ordered patterns within a week.
research Neuregulin3 alters cell fate in the epidermis and mammary gland
Neuregulin3 affects cell development in the skin and mammary glands.
research Membrane androgen receptors may mediate androgen reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles
HoxC genes are crucial for normal hair and nail development.
research The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice
Neurosteroids in the brain can increase or decrease seizure risk in mice.
research Palatogenesis and cutaneous repair: A two‐headed coin
Palate formation and skin healing share similar biological processes.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Evo Devo of the Vertebrates Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
research Inhibiting Biosynthesis and/or Metabolism of Progestins in the Ventral Tegmental Area Attenuates Lordosis of Rats in Behavioural Oestrus
Blocking certain brain processes reduces mating behavior in female rats.
research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D2 synthase expression in adult rats
Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds
research Local Changes in Neurosteroid Levels in the Substantia Nigra Reticulata and the Ventral Tegmental Area Alter Chronic Ethanol Withdrawal Severity in Male Withdrawal Seizure‐Prone Mice
Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.
research Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed
The ventral matrix is the main source of the nail plate.
research Paraneoplastic alopecia associated with internal malignancies in the cat
Some cats with sudden hair loss and tiredness might have cancer-related alopecia.
research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment
Finasteride affects prostate weights and pituitary activity differently with age.
research Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions
Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
research Morphological Features of External Genitalia in Hypospadiac Rat Model: 3-Dimensional Analysis
Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion
δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
research Is the metabolism of testosterone to 5α-dihydrotestosterone required for androgen action in the skin?
Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
research In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research Role of Androgen Receptor in Hypothalamic Regulation of Metabolism and Reproduction
Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.
research Expansion of specialized epidermis induced by hormonal state and mechanical strain
Nipple area expansion in mice needs both pregnancy hormones and mechanical strain.
research Androgen Receptors and Androgen-Dependent Initiation of Protein Synthesis in the Prostate
Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
research A case of feline paraneoplastic alopecia with secondary Malossezia‐associated dermatitis
Malassezia-associated dermatitis can cause itching in cats with feline paraneoplastic alopecia.
research CYSTIC ENDOMETRIAL HYPERPLASIA AND BACTERIAL ENDOMETRITIS ASSOCIATED WITH AN INTRAUTERINE FOREIGN BODY IN A GUINEA PIG WITH OVARIAN CYSTIC DISEASE
A guinea pig with ovarian cysts had a uterine infection and abnormal uterus lining due to a piece of hay inside it.
research Canine Alopecia Secondary to Human Topical Hormone Replacement Therapy in Six Dogs
Dogs exposed to their owners' hormone therapy developed hair loss, but symptoms resolved after stopping the therapy.