research Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice
Dutasteride works better than finasteride for preventing and treating prostate cancer.
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research Treatment of androgen excess in females: Yesterday, today and tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Medical treatment of male pattern alopecia (androgenic alopecia)
Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
research The Administration of Flumethasone, by Three Different Routes, its Measurement in the Plasma and Some Effects on Wool Growth in Merino Wethers
Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
research Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain
Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
research Treatment of hyperandrogenism in women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
research Alopecia areata incognita in Cronkhite-Canada syndrome
The report suggests that hair loss in Cronkhite-Canada syndrome may be caused by alopecia areata incognita, as shown by a patient's improvement with treatment.
research Evaluation of the 5α-reductase inhibitor finasteride on reproduction and gonadal development in medaka, Oryzias latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Bone density is normal in male rats treated with finasteride
Finasteride doesn't affect bone density in male rats.
research CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia
CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research The role of androgens in hormone replacement therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research A guide for building biological pathways along with two case studies: hair and breast development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research 5α-reductase inhibitors
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.
research Platelet-rich fibrin in the management of oral mucosal lesions: a scoping review
Platelet-rich fibrin shows promise for treating oral lesions but needs more research.
research Prunus mira Koehne in Sichuan, China: Recorded History as a Medicine and Food, Modern Applications, Distribution, and Ethnobotanical Investigations
Prunus mira Koehne is valuable for hair growth and has potential for sustainable use, but needs more research and conservation.
research Diseases of the Hair and Nails
Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.
research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue1
KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
research Hair-Thread Tourniquet Syndrome: A Comprehensive Review
Early detection and removal of hair can prevent damage in hair-thread tourniquet syndrome.
research Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research The use of platelet-rich plasma (PRP) in urology
PRP shows promise in treating urological diseases but needs more research.
research Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model
Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.
research Long-term treatment with finasteride induces apoptosis and pathological changes in female mice
Finasteride causes harmful organ changes in female mice.
research Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells
Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
research Clinical use of 5α-reductase inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3
Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.
research Edible oil-producing plants in the Sinja Valley, Jumla, Nepal
Traditional knowledge of edible oil-producing plants in Sinja Valley is declining due to outmigration and sociocultural changes.