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Altered Brain And Pituitary Androgen Metabolism By Prenatal, Perinatal Or Pre- And Postnatal Finasteride, Flutamide Or Dihydrotestosterone Treatment In Juvenile Male Rats

research Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre- and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats

26 citations , November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry”

Treatment during development affects hormone balance and sexual behavior in male rats.

research Effect of neurosteroid dehydroepiandrosterone on the higher nervous activity of old non-human primates

March 2014 in “Human Physiology”

DHEA improved brain function and behavior in old monkeys and had additional health benefits.

research Meibomian Gland Dysfunction: Endocrine Aspects

6 citations , October 2011 in “ISRN Ophthalmology”

Higher testosterone and dehydroepiandrosterone sulphate levels may help diagnose meibomian gland dysfunction.

research Hypothalamic lipid metabolism and the control of food intake

November 2016 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)”

The VMH AMPK-SNS-BAT axis may help treat cachexia and obesity.

research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry

20 citations , August 2014 in “Talanta”

The method effectively measures drug impact on DHT levels in prostate treatments.

research Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α

52 citations , May 2011 in “Journal of Neuroendocrinology”

PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.

research LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent

6 citations , October 2021 in “Brain Sciences”

Dutasteride may help reduce brain inflammation and improve cognition.

research Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients

58 citations , April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology”

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy

April 2015 in “The FASEB Journal”

Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.

research Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on fetal guinea pig brain development.

63 citations , December 2010 in “Journal of Endocrinology”

Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.

research Influence of age and of testosterone on the response of male rats to parachlorophenylalanine

18 citations , September 1972 in “British Journal of Pharmacology”

PCPA induces hypersexual behavior in male rats regardless of age or castration status.

research The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation

January 2025 in “The World Journal of Men s Health”

Finasteride temporarily suppresses brain activity, but some effects last even after stopping.

research Administration of finasteride modulates depressive-like behavior in the forced swim task of male rats

January 2012

research Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress

24 citations , May 2015 in “Schizophrenia Research”

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

research Pramipexole

October 2015 in “Elsevier eBooks”

Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.

research The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches

83 citations , January 2004 in “Pharmacology & Therapeutics”

Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.

research Regulation of itch-induced scratching by nucleus accumbens dopamine receptor-expressing neurons

April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dopamine receptors in the brain influence itch-related scratching behavior.

research Changes in expression of the δ subunit of the GABA_Areceptor and in receptor function induced by progesterone exposure and withdrawal

25 citations , July 2006 in “Journal of Neurochemistry”

Progesterone affects GABA_A receptor function by altering δ subunit levels.

research Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour

11 citations , October 2010 in “Behavioural Brain Research”

Early neurosteroid changes can alter adult brain function and behavior.

research AN ATTEMPT TO ASSESS THE MAGNITUDE OF ENDOGENOUS ANDROGEN PRODUCTION IN A CASE OF THE ADRENOGENITAL SYNDROME*

9 citations , August 1952 in “The Journal of Clinical Endocrinology & Metabolism”

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.