research The Aesthetics of Follicular Transplantation
The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.
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research Topical minoxidil therapy in hereditary androgenetic alopecia
Minoxidil applied twice daily can help regrow hair in some people with hereditary baldness, with no serious side effects.
research Preparation of hair beads and hair follicle germs for regenerative medicine
Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
research Long-term follow-up of men with male pattern baldness treated with topical minoxidil
Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.
research Care of the newborn with ichthyosis
Newborns with ichthyosis need specific care based on their skin type.
research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture
Researchers created hair-inducing human cell clusters using a 3D culture method.
research NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders
The document discusses the submission of a New Drug Application (NDA) to the U.S. FDA for vepdegestrant (ARV-471), a PROTAC protein degrader targeting the estrogen receptor, by Arvinas and Pfizer. This submission is based on positive results from the Phase 3 VERITAC-2 trial and marks a significant milestone as vepdegestrant is anticipated to be the first FDA-approved PROTAC degrader. PROTACs, a novel class of molecules, selectively degrade disease-causing proteins and offer advantages over traditional small molecule inhibitors, such as mitigating off-target effects and overcoming drug resistance. Despite concerns about their large molecular weight and drug-like properties, recent clinical results have been promising. The success of PROTACs has inspired the development of other chimeric molecules for therapeutic applications.
research A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia
Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
research Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats
FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
research The Transverse Anatomy of Androgenic Alopecia
The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research HAIR LOSS IN WOMEN
Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
research The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis
Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
research Is androgenetic alopecia a risk for atherosclerosis?
Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.
research The Contribution of Endogenous and Exogenous Factors to Male Alopecia
Genetic and environmental factors, like smoking and exercise, affect male hair loss.
research ‘Follicular Swiss cheese’ pattern - another histopathologic clue to alopecia areata
Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
research Androgenetic alopecia and risk of prostate cancer: A systematic review and meta-analysis
Vertex pattern hair loss linked to higher prostate cancer risk.
research The risk of coronary heart disease in men with androgenetic alopecia
Bald men may have higher heart disease risk.
research Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study
Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.
research Acquired Progressive Kinking of Hair
Acquired Progressive Kinking of Hair is likely an early sign of male pattern baldness.
research The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia
Finasteride and dutasteride effectively stop or reverse hair loss in women with androgenetic alopecia, with dutasteride being more effective for women under 50.
research Evaluation of Hair Density and Hair Diameter in the Adult Thai Population Using Quantitative Trichoscopic Analysis
Thai people's hair density decreases with age and varies by scalp area, but hair thickness stays the same regardless of age or scalp area.
research Cutaneous adverse effects of BRAF inhibitors in metastatic malignant melanoma, a prospective study in 20 patients.
BRAF inhibitors for melanoma often cause skin side effects, but they can be managed with proper care.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research Drug-induced hair colour changes
Some medications can change hair color, especially chloroquine and cancer treatments.
research Familial Nonmembranous Aplasia Cutis of the Scalp
Some families have a genetic condition where they are born with irregular scalp defects.
research Psychotropic Medication and Drug-Related Alopecia
Some psychiatric medications can cause reversible hair loss.
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
research Rippled‐pattern trichomatricoma
A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
research Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer
Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.