![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/assets/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
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research Lack of effect of topical finasteride suggests an endocrine role for dihydrotestosterone
Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
research Clinical picture of infectious syphilis
The document concludes that syphilis has varied symptoms that are often missed, making clinical awareness crucial for diagnosis.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Contact Alopecia: Improvement of Alopecia with Discontinuation of Fluocinolone Oil in Individuals Allergic to Balsam Fragrance
Stopping the use of fluocinolone oil containing balsam fragrance improved hair regrowth in children allergic to it.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Fatal Toxic Epidermal Necrolysis Associated with Minoxidil
Minoxidil can cause deadly skin reaction; monitor patients closely.
research Emerging lipid–polymer hybrid nanoparticles for genome editing
Lipid–polymer hybrid nanoparticles can improve genome editing delivery and outcomes.
research A case report of tinea capitis in infant in first year of life
An infant with scalp fungus was cured after extended treatment with antifungal medication.
research Androgens and erythropoiesis. Induction of erythropoietin-hypersecretory state and effect of finasteride on erythropoietin secretion
Androgens increase EPO production, finasteride doesn't significantly impact it.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
research Bone density is normal in male rats treated with finasteride
Finasteride doesn't affect bone density in male rats.
research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats
CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
research Acute localized exanthematous pustulosis due to metronidazole
A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.
research Post-finasteride syndrome – does it really exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research The investigation of the possible relationship between Coxsackie viruses and pemphigus
No link found between Coxsackie viruses and pemphigus.
research Videodermoscopy does not enhance diagnosis of scalp contact dermatitis due to topical minoxidil
Dermoscopy can't help doctors identify scalp irritation caused by topical minoxidil.
research Thermographic Follow-up of a Mild Case of Herpes Zoster
Thermography matched the patient's pain levels in a shingles case and might help diagnose shingles without a rash.
research Androgenic alopecia may have evolved to protect men from prostate cancer by increasing skin exposure to ultraviolet radiation
Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Skin deposition and permeation of finasteridein vitro: effects of propylene glycol, ethanol and sodium lauryl sulfate
Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
research Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray
Specific genes influence hair and cashmere growth in Laiwu black goats.
research Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Hormonal control of 5.ALPHA.-reductase activity in hamster sebaceous glands.
Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Two Dogs with Juvenile-Onset Skin Diseases with Involvement of Extremities
The analyses helped identify different skin diseases in the two dogs.
research Silver nanoparticles in medicine and technology: Synthesis, functionality and future prospects
Silver nanoparticles are useful in medicine and technology for their antibacterial properties and potential in drug delivery and dentistry.
research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
research Cutaneous Mastocytosis Associated With Congenital Alopecia
A 3-year-old girl with skin mast cell buildup and congenital baldness improved with treatment, suggesting a rare link between these conditions.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.