63 citations
,
February 2010 in “Journal of Neurophysiology” Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
62 citations
,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
61 citations
,
April 2021 in “Frontiers in Medicine” Hidradenitis suppurativa severely impacts quality of life, especially with severe symptoms and certain comorbidities, and current treatments don't significantly improve it.
56 citations
,
July 2014 in “PloS one” SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
55 citations
,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
54 citations
,
January 2009 in “Development” β-catenin, Shh, and Bmp signaling control hair follicle development.
52 citations
,
January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
51 citations
,
January 2024 in “Burns & Trauma” Engineered extracellular vesicles can improve tissue repair and regeneration.
51 citations
,
October 2019 in “Cells” Baricitinib reduces inflammation and improves cell health in premature aging cells.
50 citations
,
January 2013 in “Indian Journal of Dermatology” Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.
49 citations
,
December 2022 in “Pharmacological Reviews” Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
49 citations
,
October 2022 in “PubMed” Hair loss is influenced by genetics, diet, and lifestyle, but more research is needed on nutrition's role.
48 citations
,
September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
46 citations
,
August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
45 citations
,
January 1986
45 citations
,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
44 citations
,
November 2022 in “Frontiers in Immunology” TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
44 citations
,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
41 citations
,
July 2019 in “Clinical Cosmetic and Investigational Dermatology” The skin's immune system helps it regenerate and fight infections.
39 citations
,
April 2023 in “Science Advances” CD34+ cells help heal damaged limbs by promoting blood vessel growth.
38 citations
,
January 2020 in “Journal of Experimental Botany” Moderate water stress helps rice form rhizosheaths by affecting hormone responses, which may aid in breeding drought-resistant rice.
37 citations
,
December 2020 in “PLANT PHYSIOLOGY” A mutant FERONIA gene affects root hair growth at high temperatures.
37 citations
,
November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
36 citations
,
March 2014 in “Cell death and differentiation” Disrupting β-catenin signaling in certain cells causes anorectal malformations.
33 citations
,
February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
31 citations
,
December 2023 in “Middle East Fertility Society Journal” PCOS is linked to inflammation, and certain markers could help in its treatment.
31 citations
,
August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
31 citations
,
January 2019 in “Frontiers in Veterinary Science” Laser therapy improved surgical scar healing in dogs.
31 citations
,
July 2023 in “Nutrients” Vitamin D may help reduce thyroid antibodies and improve thyroid function in Hashimoto's Thyroiditis.
30 citations
,
January 2016 in “BioMed Research International” Corilagin is the main antitumor component in Phyllanthus niruri, effective against cancer cells.