research P13 DMARD preconception counselling and reinforcement should be a norm in all rheumatology clinics
Rheumatology clinics should always provide preconception counseling for women on DMARDs.
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780-810 / 1000+ results research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
research Clinical experiences on alopecia areata treatment with tofacitinib: A study of 63 patients
Tofacitinib is effective and safe for long-term treatment of severe alopecia areata, with many patients achieving complete hair regrowth.
research Spectrophotometric method for the estimation of finasteride in tablets
A new method accurately measures finasteride in tablets using color change and light absorption.
research Anthelminthic drugs
Some people have severe allergic reactions to anthelminthic drugs, but these are often due to the parasites, not the drugs.
research Development of Stable and Simple Finasteride 333-μg/mL Suspensions that Minimize Occupational Exposure.
A stable and simple finasteride suspension was developed that retains over 94.3% of its concentration for up to 90 days and doesn't significantly increase occupational exposure, but safety measures are still advised.
research Mesotherapy with bicalutamide for female pattern hair loss
Mesotherapy with bicalutamide has limited effectiveness for female hair loss.
research Finasteride, a 5alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat
Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
research Scalp Rosacea Treated with Topical Ivermectin
Topical ivermectin may help treat scalp rosacea.
research Valproate in the Treatment of Persistent Chronic Daily Headache. An Open Label Study
Valproate significantly improved headaches in two-thirds of patients.
research 51840 Efficacy of the Oral JAK1/JAK2 Inhibitor Deuruxolitinib in Adult Patients with Moderate to Severe Alopecia Areata: Pooled Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 and THRIVE-AA2 Phase 3 Trials
Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.
research Efficacy of tofacitinib as an induction agent in severe alopecia areata compared to oral betamethasone weekly pulse
Tofacitinib is effective for severe alopecia areata, similar to oral betamethasone.
research Rapid hair regrowth in an alopecia universalis patient with deucravacitinib: A case report
A new treatment called deucravacitinib helped a patient with severe hair loss grow their hair back quickly.
research Tofacitinib 2% ointment, a topical Janus kinase inhibitor, for the treatment of alopecia areata: A pilot study of 10 patients
Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.
research Anagen Effluvium
Anagen effluvium is a reversible condition causing sudden hair loss, often due to chemotherapy or head radiation.
research Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness
A new delivery system makes Curcumin more effective and safer against viruses.
research Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model
Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.
research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1
A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
This study introduces a finite element analysis (FEA)-guided framework for designing separable bubble microneedles (BMNs) that optimize geometry and cavity parameters for controlled tip separation and robust insertion. The study tested minoxidil sulfate-loaded BMNs (MXS-BMNs) and insulin-loaded BMNs (INS-BMNs) for transdermal and sublingual delivery, respectively. The BMNs demonstrated effective payload release, with over 80% liberated within 10 minutes. In ex vivo tests, MXS-BMNs showed significantly higher minoxidil permeation compared to topical gel, and in vivo tests on mice showed accelerated hair regrowth. INS-BMNs effectively lowered glucose levels in diabetic rats, comparable to subcutaneous injections. This approach reduces empirical iteration, facilitating the development of efficient microneedle systems for rapid drug delivery.
research Dermatophytic Granuloma Caused by Microsporum canis in a Heart-Lung Recipient
Fluconazole is the preferred treatment for deep skin infections in immunocompromised patients.
research Tinea Incognito
The man's skin condition was finally identified as tinea incognito, a fungal infection.
research Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents
Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
research DIFFERENTIAL STRIPPING TECHNIQUE TO DETERMINE FINASTERIDE RETENTION IN HAIR FOLLICLES AFTER IN VITRO TOPICAL APPLICATION
research Finasteride
research Finasteride
research Finasteride
research Finasteride
research Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis
A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.
research Answer to April 2014 Photo Quiz
Kerion, a scalp fungal infection, requires lab confirmation and is treated with antifungal medication and medicated shampoo.
research Successful management of therapy-resistant chronic refractory atopic dermatitis and alopecia universalis with oral tofacitinib in a girl
Oral tofacitinib successfully treated a girl's severe skin and hair conditions.