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August 1943 in “Archives of Dermatology” Applying estradiol to skin causes local changes but not cancer.
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December 2019 in “Neurobiology of Stress” Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
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May 1999 in “PubMed” Hyperandrogenism in women can cause acne, hair growth, hair loss, irregular periods, and increase the risk of infertility and diabetes.
November 2021 in “Evidencia” Young patients using finasteride may have higher risks of anxiety, depression, and suicidal thoughts.
6 citations
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November 2010 in “International Journal of Andrology” New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
October 2025 in “F1000Research” Postmenopausal women with excess male hormones may have ovarian tumors, and surgery usually cures them.
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January 1987 in “Gynecologic and obstetric investigation” Cyproterone acetate implants were more effective at reducing facial hair and improving skin in severe hirsutism than oral treatment.
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August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
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July 2019 in “Case Reports in Obstetrics and Gynecology” A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.
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September 1973 in “PubMed” High androgen levels often cause female hirsutism and infertility.
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June 2022 in “Transgender Health” Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.
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April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New progesterone-based compounds can block male hormones.
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
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May 2020 in “Drug Development Research” Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
October 2023 in “Journal of the Endocrine Society” A woman's increased facial hair and hair loss were caused by a rare ovarian tumor, cured by surgery.
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October 2024 in “JCEM Case Reports” 5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.
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September 2018 in “Dermatologic Therapy” Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.
Testosterone therapy may help women with low sexual desire after surgical menopause.
May 2018 in “Reactions Weekly” Finasteride treatment for hair loss can cause erectile dysfunction.
March 2009 in “The Journal of Urology” Finasteride helps treat hair loss and prostate issues by blocking a hormone.
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November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
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July 1980 in “Journal of Toxicology and Environmental Health” High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
February 2026 in “Journal of Psychosexual Health” Finasteride can cause long-lasting sexual dysfunction even after stopping the drug.
June 2018 in “Journal of Clinical Periodontology” Finasteride can cause gum swelling and bleeding, but stopping the drug helps recovery.
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March 2017 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
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August 2013 in “Fertility and Sterility” Finasteride may improve sperm count in subfertile men with low sperm count.
November 2020 in “Ukraïnsʹkij žurnal sučasnih problem toksikologìï” Minoxidil lotion may harm male reproductive health.