20 citations
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June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
12 citations
,
January 2016 in “Endocrinology, diabetes & metabolism case reports” Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
24 citations
,
March 2003 in “Best Practice & Research Clinical Endocrinology & Metabolism” Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
December 2023 in “Research and reports in urology” A young man with high-grade prostate cancer had successful surgery and good recovery, highlighting the need for awareness in younger men.
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
August 2013 in “Nature Reviews Drug Discovery” New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
21 citations
,
February 2021 in “Frontiers in Endocrinology” Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
1 citations
,
July 2017 in “Cancer Research” Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.
5 citations
,
February 2022 in “Supportive Care in Cancer” Older age is the main risk factor for hemorrhagic cystitis after stem cell transplants.
8 citations
,
April 2022 in “Trends in cancer” Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.
71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
5 citations
,
September 2024 in “Stem Cell Research & Therapy” Sertoli cell transplants can reduce inflammation and improve sperm quality.
December 1997 in “Journal of The European Academy of Dermatology and Venereology” Most women with excessive hair growth have a hormonal cause.
4 citations
,
June 2025 in “Medeniyet Medical Journal” TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.
5 citations
,
August 2000 in “Archives of Pathology & Laboratory Medicine” The nodule on the woman's back was a benign hair follicle tumor, not cancer, but needed removal.
October 1995 in “Pediatric Research”
February 2021 in “Facta Universitatis” Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.
April 2016 in “The FASEB Journal” Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.
8 citations
,
June 2010 in “Plastic & Reconstructive Surgery” Complete removal of scalp tumors is crucial, but malignant cases may recur or metastasize, requiring a multidisciplinary approach and close follow-up.
83 citations
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December 2004 in “American Journal of Obstetrics and Gynecology”
5 citations
,
July 1998 in “PubMed” Excessive androgen in women can cause acne, hair growth, baldness, and PCOS, often treatable with medication.
July 2022 in “L Endocrinologo” A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.
9 citations
,
August 2019 in “Clinical genitourinary cancer” Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.
March 2021 in “AACE clinical case reports” A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.
20 citations
,
January 1999 in “Current Pharmaceutical Design” Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
3 citations
,
July 2024 in “Urology Annals” Younger Klinefelter Syndrome patients have a better chance of successful sperm extraction.
July 2024 in “Biological and Clinical Sciences Research Journal” Hormonal therapy for transgender individuals carries health risks but is a personal choice.