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Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

5ARIs effectively treat and manage BPH by reducing prostate size and symptoms.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

Hirsutism, often caused by PCOS, is treated with medication and weight loss is important for obese women with PCOS.

Imiquimod may be a better non-surgical treatment for cervical pre-cancer, but its effectiveness for vaginal pre-cancer is unclear, and it has some side effects.

Combination therapy significantly reduces testosterone and moderately reduces hair growth in women with hirsutism.

Antiandrogens might help prevent or treat COVID-19 by blocking the virus's entry into cells.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Adrenocortical carcinoma is a rare, aggressive adrenal gland cancer with a poor outlook.

Individuals with this condition often develop male traits and identities at puberty despite being raised as females.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.

Identical p53 gene mutations in different cancers suggest the need for careful treatment.

A young woman had a rare scalp tumor usually found in older women.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.

The conclusion is that hirsutism is strongly linked to PCOS and higher levels of certain hormones, but not to DHEAS, prolactin, cortisol, or TSH.

Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.

Finasteride may reduce prostate tumor cell invasion and spread.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Early detection and complete surgical removal are crucial for better outcomes in treating pilomatrix carcinoma.

Recurrent vaginal bleeding in young girls without puberty signs may require a genital exam to find hidden causes.