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Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.

Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.

EV-based drug delivery shows promise but faces challenges in standardization and scalability.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

GI197111X is best dissolved in Capmul MCM for trials.

Created microspheres show potential for safe and effective use in prostate artery embolization.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

Researchers developed a quick and reliable method to test for betamethasone dipropionate and calcipotriol in ointments and drugs.

Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

Repurposing existing drugs can quickly and cheaply find new treatments for diseases.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.

Vegan exosome-like vesicles from microalgae improve skin and hair health, reducing wrinkles and enhancing elasticity.

A reliable UV method was created to measure finasteride accurately.

Different tumor cells in one basal cell carcinoma can cause mixed treatment responses, suggesting personalized treatment is needed.

The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.

The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.

A woman developed male characteristics after using unregulated hormone therapy.

Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

Regulatory challenges make developing combination therapies in urology difficult and costly.