363 citations
,
May 2006 in “Current Opinion in Psychiatry” Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.
262 citations
,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
258 citations
,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
240 citations
,
February 2005 in “Diabetes Care” Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.
232 citations
,
January 2002 in “Mechanisms of development” Different enzymes are active in different parts of developing mouse organs.
184 citations
,
October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” Sulforaphane from broccoli can help protect skin from sun damage.
179 citations
,
December 1989 in “Medical Entomology and Zoology” Effective management of ichthyoses requires genetic counseling and appropriate treatments.
147 citations
,
January 2003 in “American journal of clinical dermatology” The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
146 citations
,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
140 citations
,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
140 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
138 citations
,
June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
133 citations
,
January 2009 in “Nature” Lgr5 and the vitamin D receptor are key in controlling skin inflammation and tumor risk in mice.
128 citations
,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
128 citations
,
January 2001 in “American Journal of Clinical Dermatology” Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
119 citations
,
January 2012 in “Nutrition & Metabolism” Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
115 citations
,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
110 citations
,
November 1984 in “The American Journal of Medicine” A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.
104 citations
,
August 2008 in “Clinics in Dermatology” Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
100 citations
,
October 1986 in “Clinical Endocrinology” Alopecia indicates more severe resistance to 1,25-dihydroxyvitamin D.
98 citations
,
October 2012 in “Dermatologic Clinics” Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.
97 citations
,
April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
95 citations
,
July 2006 in “British Journal of Dermatology” Vitamin D receptors in hair follicles change with the hair cycle, affecting hair growth.
95 citations
,
February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
92 citations
,
January 2013 in “Dermatology” Vitiligo patients often have other health issues, especially thyroid disorders.
91 citations
,
March 2021 in “Molecular and Cellular Endocrinology” CYP11A1 is crucial for skin health and disease by producing important steroids.
91 citations
,
April 2017 in “Diabetes & Metabolic Syndrome: Clinical Research and Reviews” Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.
90 citations
,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.