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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

A 15-year-old girl with rare reproductive disorders received hormone therapy to develop secondary sexual traits, but infertility persisted.

Alopecia Areata Incognita causes widespread hair thinning, and treatment with systemic corticosteroids and psychiatric support can lead to remission.

Clouston syndrome is inherited in an autosomal dominant pattern and caused by a specific gene mutation, with no current treatment available.

The study found that alopecia areata and hypothyroidism increase the risk of each other, but androgenetic alopecia and hypothyroidism do not.

Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.

Fexofenadine may help treat a difficult type of hair loss.

Early detection of specific VDR mutations is crucial for effective treatment and better dental outcomes in children with hereditary vitamin D–resistant rickets.

Thyroid tests may not be needed for all vitiligo and alopecia areata patients unless thyroid disease symptoms appear.