908 citations
,
July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
September 2019 in “Romanian Journal of Pediatrics” Fetal skin can heal without scars, offering insights for better wound treatments.
9 citations
,
August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
April 2018 in “Dermatologic Surgery” May 2007 in “Archives of Plastic Surgery” The Frechet flap technique effectively hides scalp surgery scars with good results and minimal issues.
4 citations
,
May 2013 in “Annals of Plastic Surgery” Hair transplants onto a scalp reconstruction flap improved appearance successfully.
October 2025 in “Cell Proliferation” IL10_ApoEVs improve skin healing and reduce scarring.
1 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Fibroblasts and myeloid cells in mouse skin wounds are diverse and can change into different cell types during healing.
January 2011 in “Plastic Surgery” Hair grafts successfully restored a realistic beard and hid scars, satisfying the patient.
28 citations
,
October 2024 in “Advanced Materials” Artificial skin can heal wounds without scars and regenerate hair, oil, and sweat glands.
48 citations
,
January 2018 in “Stem Cells International” Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.
7 citations
,
September 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” Occipital donor sites for skin grafts heal faster, hurt less, look better, and have fewer complications than femoral sites.
79 citations
,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
2 citations
,
September 2014 in “The American Journal of Cosmetic Surgery” Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
63 citations
,
October 2012 in “Wound Repair and Regeneration” Hair follicle grafting can help heal chronic leg ulcers.
June 2018 in “Dermatologic Surgery” January 2011 in “Journal of Tissue Engineering and Reconstructive Surgery” Using dermal papillae cells and keratinocytes in skin substitutes speeds up healing and helps form hair follicles and glands.
March 2026 in “BMC Veterinary Research” Bovine amniotic membrane with propolis helped a cat's large skin wound heal quickly and fully.
2 citations
,
June 2006 in “Experimental dermatology” Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.
1 citations
,
May 2015 in “Plastic and Reconstructive Surgery” The Sacred Heart Bilobed Flap is a surgical method for repairing small scalp defects with local flaps, relying on scalp elasticity and hair regrowth to hide any imperfections.
72 citations
,
November 2000 in “Archives of Dermatology” Excision with primary closure is an excellent treatment for extensive acne keloidalis nuchae.
October 2020 in “Plastic Surgery” Bone marrow stem cells improve healing of deep skin wounds.
April 2019 in “Journal of Investigative Dermatology” Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
16 citations
,
October 1979 in “The Journal of Dermatologic Surgery and Oncology” Scalp reduction surgery successfully reduced baldness and improved self-image in a burn victim before hair transplantation.
54 citations
,
May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
3 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
21 citations
,
February 2015 in “Journal of Feline Medicine and Surgery” Negative pressure wound therapy is effective for skin grafts in cats.