research Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice
Allopregnanolone may help prevent nicotine withdrawal symptoms.
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research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Role of allopregnanolone biosynthesis in acute stress-induced anxiety-like behaviors in mice
Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
research Mechanical characterization of curly hair: Influence of the use of nonconventional hair straightening treatments
Formaldehyde damages curly hair more than glyoxylic acid.
research Lipid Droplets from Plants and Microalgae: Characteristics, Extractions, and Applications
Plant and algal lipid droplets are promising for natural oil production but need better extraction methods.
research Serial Hydrolysis for the Simultaneous Analysis of Catecholamines and Steroids in the Urine of Patients with Alopecia Areata
A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.
research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models
The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
research ABSTRACTS—SYMPOSIA
Certain drugs can block changes in brain receptors caused by alcohol withdrawal.
research Choose the proper vehicle
Patch testing with different solvents helps find the right minoxidil formulation for those with scalp allergies.
research The Viscoelastic Properties of Chemically Modified alpha-Keratins in Human Hair
Chemical modifications can alter hair's stability and flexibility, with hydrophobic interactions helping maintain structure in humid conditions.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS
Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
research Contact dermatitis to phenol‐formaldehyde resin in two plywood factory workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research The Oxidative Degradation of Keratin (Wool and Bovine Hair)
Oxidizing agents break down keratin in wool and hair, causing swelling and increased solubility.
research Comparison of methanol and isopropanol as wash solvents for determination of hair cortisol concentration in grizzly bears and polar bears
Methanol is better than isopropanol for washing grizzly bear hair to measure cortisol.
research INHALATION TOXICITY STUDIES OF AQUEOUS DISPERSION RESIN
Aqueous dispersion resin is safe to inhale at levels below 30 mg/m³.
research Alteration of neonatal Allopregnanolone levels affects exploration, anxiety, aversive learning and adult behavioural response to intrahippocampal neurosteroids
Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.
research Long-Term Treatment with Sodium Valproate
Combining sodium valproate with other epilepsy drugs increases ammonia levels and side effects.
research Solubility of minoxidil in binary mixture of ethanol + water at various temperatures
Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.
research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research Towards sustainable and scalable synthesis of amitriptyline hydrochloride, minoxidil, and pyrrolidinyl diaminopyrimidine oxide
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Mechanisms responsible for progesterone's protection against lordosis-inhibiting effects of restraint II. Role of progesterone metabolites
Allopregnanolone, a progesterone metabolite, helps reduce restraint effects on behavior.
research Developmental Toxicity of Levo-Alpha-Acetylmethadol (LAAM) in Tolerant Rats
LAAM caused developmental toxicity in tolerant rats without causing birth defects.
research HAIR LOSS FROM SEBUM
Certain unsaturated compounds can cause temporary hair loss by affecting hair structure.
research A Raman spectroscopic investigation of the mechanism of the reduction in hair with thioglycerol and the accompanying disulphide conformational changes
Thioglycerol treatment at pH 9.0 with ammonia causes less hair damage and better waving than thioglycolic acid.
research Determination of Residual Organic Solvents in Finasteride by Headspace Capillary Gas Chromatography
A new method accurately detects tiny amounts of chloroform and dichloromethane in finasteride.
research Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate
3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
research Determination of Residual Organic Solvents in Finasteride Raw Materials by Headspace Capillary Gas Chromatography
The method effectively detects residual solvents in finasteride raw materials.