52 citations
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November 2006 in “International Journal of Cosmetic Science” Different types of wrinkles need specific treatments.
November 2025 in “Journal of Exposure Science & Environmental Epidemiology”
December 2025 in “Brazilian Journal of Hair Health” The Spiral Model helps understand hair growth changes with age and identify hair problems early.
2 citations
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December 2017 in “Skin appendage disorders” An elderly man's non-healing scalp lesion was successfully treated with a strong topical steroid.
108 citations
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January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
10 citations
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January 2017 in “Skin appendage disorders” Emotional stress can trigger intermittent hair loss in chronic telogen effluvium, which may not improve with treatment if stress continues.
27 citations
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June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
22 citations
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August 2011 in “Journal of the American Academy of Dermatology” Topical tacrolimus can effectively treat erosive pustular dermatosis and related hair loss.
January 2008 in “대한미용학회지” UV exposure severely damages hair, making it rough and weak.
4 citations
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January 2007 in “Sen'i Gakkaishi” Permed hair degrades faster and shows more damage after protease treatment compared to untreated hair.
20 citations
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May 2009 in “Health physics” The model helps predict uranium levels in human hair from drinking contaminated water, offering an alternative to urine tests.
May 2026 in “International Journal of Cosmetic Science” UV radiation damages hair similar to bleaching, but double bleaching causes more severe protein degradation.
1201 citations
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January 2010 in “Science” Active and quiescent stem cells work together in mammals to maintain and repair tissues.
695 citations
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October 2011 in “Cell stem cell” Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
266 citations
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January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
249 citations
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November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
214 citations
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April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
180 citations
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January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
169 citations
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February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
114 citations
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January 2016 in “Current topics in developmental biology/Current Topics in Developmental Biology” Frizzled receptors are essential for various body development processes and maintaining certain body functions.
106 citations
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February 2014 in “eLife” Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
91 citations
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December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
91 citations
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June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
87 citations
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March 2015 in “The EMBO Journal” Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
85 citations
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January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
82 citations
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July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
79 citations
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November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
75 citations
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September 2016 in “EMBO journal” PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.