218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
198 citations
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July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
177 citations
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July 2004 in “The Journal of Sexual Medicine” Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.
159 citations
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July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
159 citations
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September 2001 in “European Journal of Cancer Care” Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
146 citations
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June 2012 in “PLoS ONE” Paneth cells help support stem cells and aid tissue regeneration after injury.
134 citations
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January 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
120 citations
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
86 citations
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February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
85 citations
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April 2007 in “Dermatologic Clinics” Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.
77 citations
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June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
76 citations
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January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
74 citations
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April 2005 in “Dermatologic Clinics” Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
67 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
67 citations
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October 2005 in “Annals of Oncology” Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.
61 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.
58 citations
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March 2013 in “Human Reproduction Update” Products should be called 'sperm-safe' only after thorough, well-designed tests.
54 citations
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September 2012 in “Dermatologic Clinics” Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.
52 citations
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May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
51 citations
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March 2014 in “Nature Communications” Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
49 citations
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July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
48 citations
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February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
41 citations
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August 2024 in “Drug Delivery and Translational Research” 3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
41 citations
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February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
40 citations
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December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
39 citations
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March 2003 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” Behavioral dermatology treats skin problems by considering both emotional and physical factors.
38 citations
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April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.