research Controlling the stem cell niche: right time, right place, right strength
Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
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research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway
Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
research Molecular Genetics of Alopecias
Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.
research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq
WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
research Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway
rRSPO1 protein boosts hair growth by activating a key signaling pathway.
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research In silico analysis of gene expression data from bald frontal and haired occipital scalp to identify candidate genes in male androgenetic alopecia
Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
research Expression ofWise in chick embryos
The molecule Wise is involved in the development of various structures in chick embryos.
research Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture
Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
research Sodium pentaborate pentahydrate promotes hair growth through the Wnt/β-catenin pathway and growth factors
Sodium pentaborate pentahydrate can increase hair growth and improve hair quality at certain doses.
research Pathomechanism of androgenetic alopecia and new treatment
Male pattern baldness is caused by certain cells in hair follicles and could potentially be treated by targeting a specific growth factor, TGF-β1.
research Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation
Photobiomodulation helps protect hair follicle cells from damage caused by DHT.
research Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells
Diphlorethohydroxycarmalol may help treat hair loss better than current medications.
research Novel Androgen Receptor Gene Variant Containing a Premature Termination Codon in a Patient with Androgen Insensitivity Syndrome
A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
research Emerging pharmacotherapies and regenerative solutions for promoting hair growth for androgenetic alopecia
New treatments for hair loss show promise but need more testing for effectiveness and safety.
research Harnessing miRNA Milk-Derived Exosomes for Hair Loss Disorders: In Vitro Modulation of WNT Signaling and Dermal Papilla Proliferation
Milk-derived exosomes may help treat hair loss by boosting hair follicle growth.
research Integrative Whole-Transcriptome Sequencing Analysis of Skin Tissues with Different Coat Types in Cashmere Goats Across Stages of Hair Follicle Development
The study found that different genes are active in cashmere goats' hair growth stages, which can help improve cashmere production.
research 0846 Wnt signaling drives hair follicle regeneration in wounds by attenuating mechanotransduction in the epidermis
Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.
research Isoalantolactone (ISA) Stimulates Hair Cell Growth Through Activation of the WNT/β-catenin and Ras/MAPK Pathways
Isoalantolactone promotes hair growth by activating specific cell pathways.
research Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation
Meloside A may help protect hair cells from damage linked to hair loss.
research LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway
H19 may help prevent hair loss by keeping hair cells young.
research Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity
Maslinic acid from olive extracts promotes hair growth like minoxidil.
research Ellagic acid inhibits dihydrotestosterone-induced ferroptosis and promotes hair regeneration by activating the Wnt/β-catenin signaling pathway
Ellagic acid may help regrow hair and prevent hair loss by activating a specific cell growth pathway.
research Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research The FRZB gene regulates hair follicle development in rabbits via the Wnt/β-catenin signaling pathway
The FRZB gene slows hair growth in rabbits.
research Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/β-Catenin Pathway
Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
research mTOR signaling in hair follicle and hair diseases: recent progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Melatonin regulates the periodic growth of secondary hair follicles through the nuclear receptor RORα
Melatonin helps hair grow by activating the RORα receptor in goats.
research Natural product Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration
Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.