research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
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research Regeneration of fat cells from myofibroblasts during wound healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning
Changing how mesenchymal stromal cells are grown can improve their healing abilities.
research Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling
Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
research Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation
Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
research Vitamin D and the skin: Physiology and pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research Exosomes for repair, regeneration and rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Regulation of hair follicle development by exosomes derived from dermal papilla cells
Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
research Exosomes and Their Bioengineering Strategies in the Cutaneous Wound Healing and Related Complications: Current Knowledge and Future Perspectives
Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research Hair follicle stem cell cultures reveal self‐organizing plasticity of stem cells and their progeny
The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
research Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury
Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice
Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss
Laser treatment can stimulate hair growth for male pattern hair loss.
research Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth
Injecting a special gel with human protein particles can help hair grow.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Signalling by senescent melanocytes hyperactivates hair growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research Developing stratified epithelia: lessons from the epidermis and thymus
The skin and thymus develop similarly to protect and support immunity.
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
research LncRNAs in Secondary Hair Follicle of Cashmere Goat: Identification, Expression, and Their Regulatory Network in Wnt Signaling Pathway
Researchers found that certain RNA molecules might play a role in the growth of Cashmere goat hair.
research The role of R-spondins and their receptors in bone metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.