Search

for
Search:

Did you mean Wnt-1?

GlossaryWnt-1

protein crucial for cell signaling in hair follicle development

Wnt-1 is a protein that plays a crucial role in cell signaling pathways, which are essential for various developmental processes, including the growth and maintenance of hair follicles. It is part of the Wnt family of proteins that regulate cell-to-cell interactions during embryogenesis and are also involved in the regulation of stem cells in adult tissues.

Related Terms

Sort by

Research

30 / 1000+ results

Exosome-Derived Long Non-Coding RNA AC010789.1 Modified by FTO and hnRNPA2B1 Accelerates Growth of Hair Follicle Stem Cells Against Androgen Alopecia by Activating S100A8/Wnt/β-Catenin Signaling

research Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐catenin signalling

January 2025 in “Clinical and Translational Medicine”

A specific RNA can help hair growth in baldness by boosting stem cell activity.

research Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation

32 citations , August 2015 in “Journal of Investigative Dermatology”

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Nature-Derived Lignan Compound VB-1 Exerts Hair Growth-Promoting Effects by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells

research Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells

17 citations , May 2018 in “PeerJ”

VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.

Efficacy of 1,550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia

research Efficacy of 1,550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia

10 citations , August 2018 in “Dermatologic Surgery”

Laser treatment improves hair density and increases growth factors in androgenetic alopecia.

research The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice

July 2025 in “Frontiers in Pharmacology”

G-1 promotes hair growth in female mice by activating specific signaling pathways.

Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells

research Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells

3 citations , February 2022 in “Frontiers in Genetics”

The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.

research OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis

9 citations , October 2013 in “Journal of Investigative Dermatology”

The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.

Canonical Wnt-10b Signaling Exerts an Ability to Maintain Mouse Dermal Papilla Cells

research Canonical Wnt-10b signaling exert an ability of maintaining mouse dermal papilla cells

September 2016 in “Journal of Dermatological Science”

Wnt-10b is important for keeping mouse skin cells healthy for hair growth.

Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia

research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia

47 citations , October 2016 in “Molecular and Cellular Endocrinology”

Androgens prevent hair growth by changing Wnt signals in cells.

research The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin

42 citations , March 2014 in “European Journal of Pharmacology”

Ginsenoside F2 from ginseng may increase hair growth better than standard treatments by affecting cell growth signals.

research Malva verticillataseed extracts upregulate the Wnt pathway in human dermal papilla cells

25 citations , August 2015 in “International Journal of Cosmetic Science”

Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.

Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway

research Randomized trial of electrodynamic microneedling combined with 5% minoxidil topical solution for treating androgenetic alopecia in Chinese males and molecular mechanistic study of the involvement of the Wnt/β-catenin signaling pathway

10 citations , May 2020 in “Journal of Dermatological Treatment”

Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.

research Role of the Wnt signaling pathway in keratoacanthoma

2 citations , November 2019 in “Cancer reports”

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway

research 3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway

February 2026 in “International Journal of Molecular Sciences”

3-Hydroxypropionic acid may help treat hair loss by promoting hair growth in cells.

Astragalus Membranaceus and Cinnamomum Cassia Stimulate Hair Follicle Differentiation-Related Growth Factor via Wnt/Beta-Catenin Pathway

research Astragalus membranaceus and Cinnamomum cassia Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway

October 2023 in “Current Issues in Molecular Biology”

The YH complex, made from Astragalus membranaceus and Cinnamomum cassia, may help treat hair loss by promoting hair growth and follicle development.

Garlic Exosomes Promote Hair Growth Through the Wnt/Beta-Catenin Pathway and Growth Factors

research Garlic Exosomes Promote Hair Growth Through the Wnt/β-catenin Pathway and Growth Factors

July 2023 in “Cureus”

Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.

Platelet-Rich Plasma Contains High Concentrations of DKK1, A Potent Inhibitor of Wnt Signaling That Limits Bone Regeneration and Hair Growth

research Platelet-Rich Plasma Contains High Concentrations of DKK1, A Potent Inhibitor of Wnt Signaling that Limits Bone Regeneration and Hair Growth

January 2023 in “Journal of orthopedics & bone disorders”

Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.

Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice

research Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice

23 citations , January 2018 in “International Journal of Molecular Medicine”

Baicalin helps hair growth by activating specific cell signals and pathways.

research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells

8 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.

research Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately

113 citations , June 2015 in “Stem Cell Research & Therapy”

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

research Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways

45 citations , August 2009 in “American Journal Of Pathology”

Noggin promotes skin tumors by activating certain cell signaling pathways.

Novel Small Molecules Downregulate CDK1 Expression and Inhibit Wnt/β-Catenin Signaling in Cutaneous Squamous Cell Carcinoma by Targeting Its Distinct Tumor-Specific Cellular Landscape

research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape

September 2025 in “Experimental & Molecular Medicine”

Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.

research Mechanical stretch induces hair regeneration through the alternative activation of macrophages

163 citations , April 2019 in “Nature Communications”

Mechanical stretching of the skin can promote hair growth by activating certain immune cells.

research New drugs under investigation for the treatment of alopecias

26 citations , January 2019 in “Expert Opinion on Investigational Drugs”

New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.

research 3D printing of microneedle arrays for hair regeneration in a controllable region

16 citations , January 2023 in “Molecular Biomedicine”

3D-printed microneedles can precisely regrow hair in targeted areas.

research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives

9 citations , August 2024 in “International Journal of Molecular Sciences”

Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.

research Regulatory role of LEF-1 in the proliferation of Arbas White Cashmere goat dermal papilla cells

9 citations , April 2018 in “Canadian Journal of Animal Science”

LEF-1 boosts cell growth in goat hair follicles, aiding cashmere production.

$Human Keratinocytes Derived from the Bulge Region of Hair Follicles Are Refractory to Differentiation$

research Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation

8 citations , April 2009 in “International journal of oncology”

Hair follicle cells resist turning into skin cells.

research Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways

5 citations , March 2022 in “Frontiers in Medicine”

PRP is effective for treating hair loss, especially with other treatments.

Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

5 citations , September 2021 in “Frontiers in Cell and Developmental Biology”

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.