research Regulatory effect of β-catenin on proliferation of hair follicle stem cells involves PI3K/Akt pathway
β-catenin helps hair follicle stem cells grow by activating a specific cell pathway.
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research Androgens downregulate BMP2 impairing the inductive role of dermal papilla cells on hair follicle stem cells differentiation
Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
research Discovery of genes and proteins possibly regulating mean wool fibre diameter using cDNA microarray and proteomic approaches
Researchers identified genes and proteins that may influence wool thickness in sheep.
research Vitamin D metabolism and function in the skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Comparative Evaluation of the Clinical Efficacy of PRP-Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia
PRP therapy and minoxidil combo works best for male hair loss.
research Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells
Nonanal from fruits and vegetables promotes hair growth by increasing growth factors.
research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Efektivitas Terapi Minoksidil pada Alopesia Androgenetik: Studi in Vivo
5% minoxidil significantly increases hair follicle density.
research Topical sodium valproate-loaded nanospanlastics versus conventional topical steroid therapy in alopecia areata: a randomized controlled study
Both treatments for alopecia areata showed similar modest effectiveness.
research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents
Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
research Extraskeletal actions of vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research The cycling hair follicle as an ideal systems biology research model
The hair follicle is a great model for research to improve hair growth treatments.
research Follicular Map: A Novel Approach to Quantitative Trichoscopy
The new Follicular Map method could help assess hair treatment effectiveness but has some limitations.
research Computational derivation of a molecular framework for hair follicle biology from disease genes
The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
research A transient dermal niche and dual epidermal programs underlie sweat gland development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.
research 197 A novel splice site mutation in LIPH identified in a Japanese patient with autosomal recessive woolly hair
Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
research 196 The endocannabinoid tone regulates human sebocyte biology
The endocannabinoid system affects oil production and inflammation in skin cells.
research 194 An underlying mechanism of hair loss in acrodermatitis enteropathica
Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.
research 192 MicroRNAs and their regulatory interactions in the human hair follicle
The research found that certain microRNAs are important for human hair growth and health.
research 193 Unveiling the role of estradiol in the pathogenesis of female pattern hair loss
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research Vitamin D and the skin: Physiology and pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
research Androgenetic alopecia: An update
Minoxidil and finasteride effectively treat hair loss.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4
Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
research Genetics and other factors in the aetiology of female pattern hair loss
Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review
Some plants with flavonoids may help treat hair loss and promote hair growth.