research Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators
Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
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research The efficacy and safety of 5α-reductase inhibitors in androgenetic alopecia: a network meta-analysis and benefit–risk assessment of finasteride and dutasteride
Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
research From Axioms to New Insights into Dandruff
Dandruff is a common, winter-worsened scalp condition linked to inflammation and microorganisms, treatable with products like ketoconazole, and may affect hair loss.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?
Low iron and vitamin D levels are linked to hair loss in women.
research Autoimmune Polyglandular Syndrome Type 1 in Russian Patients: Clinical Variants and Autoimmune Regulator Mutations
Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
research Epidermal stem cells: practical perspectives and potential uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Is Androgenetic Alopecia a Photoaggravated Dermatosis?
Sunlight worsens hair loss; protect scalp.
research The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation
Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
research HAIR ANALYSIS FOR DRUGS OF ABUSE. PLAUSIBILITY OF INTERPRETATION
Hair analysis can detect drug use but requires careful interpretation due to its complexity.
research Topical Use of Minoxidil in Children and Systemic Side Effects
Minoxidil use in children may cause heart issues.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine
Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
research A Prospective Study of Cutaneous Adverse Events Induced by Low-Dose Alpha-Interferon Treatment for Malignant Melanoma
Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.
research A case series of 20 women with hidradenitis suppurativa treated with spironolactone
Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
research 46,XY DSD due to impaired androgen production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Female pattern hair loss in complete androgen insensitivity syndrome
Hair loss in women may have causes other than hormones.
research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Androgenetic alopecia in the paediatric population: a retrospective review of 57 patients
Alopecia common in teens, may indicate endocrine issue, minoxidil effective treatment.
research Hair Loss Pattern due to Chemotherapy-Induced Anagen Effluvium: A Cross-Sectional Observation
Chemotherapy often causes patterned hair loss, with some scalp areas more resistant to hair loss than others.
research Type 1 interferon signature in the scalp lesions of alopecia areata
Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
research EEMCO Guidance for the Assessment of Hair Shedding and Alopecia
The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research Alopecia Areata in Severe Atopic Dermatitis Treated With Dupilumab
Dupilumab may cause hair loss in some patients with severe atopic dermatitis.
research Drug-induced alopecia after dupilumab therapy
Dupilumab may cause significant hair loss, which can reverse after stopping the drug.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Family History and Risk of Hair Loss
Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.
research Primary Generalized Glucocorticoid Resistance and Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.