35 citations
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January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
1 citations
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February 2002 in “The Lancet” Keratinocytes might turn into stem cells, but more research is needed to confirm this.
June 2024 in “Current Developments in Nutrition” Diet changes can improve skin health by altering the immune response and skin microbiome.
39 citations
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April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
182 citations
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May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
176 citations
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
53 citations
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August 2010 in “Molecular Carcinogenesis” Slug is crucial for skin health, hair growth, and healing.
44 citations
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July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
25 citations
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September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
23 citations
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May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
13 citations
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August 2020 in “Frontiers in Immunology” Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
8 citations
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July 2024 in “Cells” PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
1 citations
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June 2015 in “Experimental Dermatology” Fat may help skin health and repair, but more research is needed.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
May 2015 in “Immunology Endocrine & Metabolic Agents - Medicinal Chemistry” Vitamin D and calcium are essential for effective wound healing.
58 citations
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December 2000 in “Experimental Dermatology” Involucrin is a useful marker for keratinocyte differentiation in mice.
26 citations
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August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
35 citations
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April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
37 citations
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August 2024 in “Current Issues in Molecular Biology” Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
27 citations
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May 2024 in “Clinical and Translational Medicine” Melanocyte stem cells are vital for skin and hair color and have potential in treating skin disorders and cancer.
10 citations
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May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
10 citations
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June 2016 in “Cell Transplantation” Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
July 2013 in “University of Southern California Digital Library” New stem cells in nails and sweat glands can regenerate skin and hair.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
4 citations
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June 2021 in “Wounds-a Compendium of Clinical Research and Practice” Chronic scalp lesions with crusts and pus that heal with strong topical steroids suggest Erosive Pustular Dermatosis, confirmed by biopsy showing specific immune cells.
28 citations
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October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
MSC-CM cream speeds up burn wound healing better than the control treatment.