research Selenium In Thioredoxin Reductase: Resistance To Oxidative Inactivation, Oxidation States, And Reversibility Of Chemical Reactions
Selenium in proteins helps prevent over-oxidation and supports chemical reversibility.
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research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Engineered Janus hydrogels: biomimetic surface engineering and biomedical applications
Janus hydrogels improve medical adhesives by mimicking natural barriers for better tissue integration.
research Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors
research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research Extraction of follicular horny impactions of the face by polymers. Efficacy and safety of a cosmetic pore-cleansing strip (Bioré)
Bioré Pore Perfect strips effectively and safely clean pores on the nose.
research A Dispute Between the Cavendish and Caltech: The Emergence and Ubiquity of the α-Helix
The alpha-helix was confirmed as a key structure in proteins.
research B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy
Boron/nitrogen-doped carbon nano-onions improve targeted breast cancer treatment by enhancing drug delivery and reducing side effects.
research Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis
Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
research Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Microneedle patches with different pore sizes can effectively deliver drugs and trigger strong immune responses.
research Lidocaine-Loaded Solid Lipid Microparticles (SLMPs) Produced from Gas-Saturated Solutions for Wound Applications
Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
research Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies
The gel is a safe and effective treatment for hyperpigmentation.
research Engineered exosomes and composite biomaterials for tissue regeneration
Exosomes show promise for future tissue regeneration.
research A new catalyst for organic synthesis: mercuric triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research White piedra: further evidence of a synergistic infection
White piedra is often a co-infection with a specific bacterial infection.
research Optimization of minoxidil microemulsions using fractional factorial design approach
The study found a way to improve a skin-applied minoxidil formula using a specific design method.
research Monilethrix: an ultrastructural study
Monilethrix hair issues are due to problems in the hair's internodes.
research Leucine-activated nanohybrid biofilm for skin regeneration via improving cell affinity and neovascularization capacity
The biofilm enhances skin healing by promoting cell growth and blood vessel formation.
research P381 Kinetics of Titan cells generation and transcriptome modifications comparing three in vitro protocols
Three different methods were compared for creating Titan cells, a type of fungus cell. The OZ method made the most cells initially, but the number dropped quickly. The EB method also made a lot of cells, but the number also dropped. The AA method made fewer cells, but the number stayed steady. The methods also affected which genes were active in the cells.
research Electroosmotic pore transport in human skin.
research New ethanol and propylene glycol free gel formulations containing a minoxidil-methyl-β-cyclodextrin complex as promising tools for alopecia treatment
New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
research Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion
Finasteride helps prevent kidney stones, but side effects need more research.
research The Effect of Leonuri Herba alkaloids on Senile BPH (male and female hormone induced) model rats
Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.
research 6450 Leydig Cell Tumor: A Rare Cause of Post-menopausal Hyperandrogenism
Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.
research Eosinophilic folliculitis with multifocal distribution in a dog
The dog's skin condition improved quickly with treatment and did not return.
research Mechanistic Approach on the Pulmonary Oxido-Inflammatory Stress Induced by Cobalt Ferrite Nanoparticles in Rats
Daily intake of 0.5 or 5 mg cobalt ferrite nanoparticles can harm lungs through oxidative and inflammatory stress.
research Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Consequences of Skin Barrier Dysfunction
A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
research Crystal Structure of 17-.BETA.-Benzoyloxy-16-.BETA.-methylpregna-4,6-diene-3,20-dione.
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research S5550 Zinc Induced Liver Failure From Remedy to Ruin: Zinc Overload and Liver Failure
Excessive zinc intake can cause liver failure.
research Clinical efficacy and safety of Kanglaite injection, adjuvant cemcitabine and cisplatin chemotherapy for advanced non-small-cell lung cancer: A systematic review and meta-analysis
Kanglaite injection with chemotherapy improves treatment and reduces side effects for advanced lung cancer.