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Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

6 citations , September 2015 in “Journal of Medicinal Chemistry”

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

research Lead, Copper, Zinc, and Magnesium Content in Hair of Children and Young People with Some Neurological Diseases

29 citations , January 2002 in “Biological Trace Element Research”

research Unravelling the molecular basis for symbiotic signal transduction in legumes

27 citations , March 2006 in “Molecular Plant Pathology”

Legumes use flavonoids to start a process with rhizobia for nitrogen fixation, involving specific genes and proteins.

research Herpes Zoster Precipitating First Attack of Neuromyelitis Optica along with Perinuclear Anti-Neutrophilic Cytoplasmic Antibody Positive Vasculitis

June 2022 in “Annals of Indian Academy of Neurology”

A woman's shingles infection triggered her first episode of a rare neurological disorder and blood vessel inflammation.

research Interaction of the vacuolar H+-pyrophosphatase AVP1 with the secondary transporters AtNHX1 and SOS1 in Arabidopsis thaliana: Implications in salt tolerance and mineral nutrition

January 2006 in “OpenCommons at University of Connecticut (University of Connecticut)”

Overexpressing AVP1 and AtNHX1 in plants improves salt tolerance and root hair development.

research A completely polyherbal conditioning and antioxidant shampoo: A phytochemical study and pharmaceutical evaluation

25 citations , January 2019 in “Journal of Pharmacy And Bioallied Sciences”

The herbal shampoo is a chemical-free, nourishing product with excellent conditioning, cleansing, and antimicrobial effects.

research PIXE microanalysis in green hair

January 1989

Copper levels in green hair decreased significantly after treatment.

Development and Evaluation of Biofabricated Silver Nanoparticles from Blumea Lacera for In Vitro Antibacterial, Antioxidant, and Anti-inflammatory Activity

research Development and Evaluation of Bio fabricated Silver Nanoparticles from Blumea lacera for In-vitro Antibacterial, Antioxidant and Anti-inflammatory Activity

2 citations , April 2023 in “Pharmacognosy Journal”

Herbal silver nanoparticles from Blumea lacera showed strong antibacterial and anti-inflammatory effects.

research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor

1 citations , August 2021 in “Journal of Investigative Dermatology”

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

research Natural ‘Green’ Sugar-Based Treatment for Hair Styling

February 2022 in “Fibers”

Scientists created a non-toxic, sugar-based hair product that can style hair without damage.

research A double blind, randomised, vehicle-controlled, safety and tolerance study of topical PSK 3841 solution at 5% administered twice daily over four weeks to healthy Caucasian males with androgenetic alopecia

December 2012 in “http://isrctn.org/>”

research Comparación de los efectos del D-004, imipramina y sertralina en el modelo de nado forzado en ratones Comparative effects of D-004, Imipramine and Sertraline in the forced swimming test in mice

September 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)”

D-004 shows moderate antidepressant effects but is less effective than Sertraline and Imipramine.

research Evidence for calcium soaps in human hair shaft revealed by sub-micrometer X-ray fluorescence

7 citations , March 2003 in “Journal de Physique IV (Proceedings)”

Calcium soaps are present in human hair and can be removed with acid.

research DOSE DEPENDENT INHIBITORY EFFECT OF LAGENARIA SICERARIA FRUIT POWDER ON FSH AND LH HORMONES IN MALE WISTAR RATS

February 2018 in “Zenodo (CERN European Organization for Nuclear Research)”

High doses of Lagenaria siceraria fruit powder lower FSH and LH hormone levels in male rats.

Development of Topical Formulations Containing 20% Zinc Oxide Nanoparticles: Stability Assessment and Penetration Evaluation

research Development of Topical Formulations Containing 20% of Coated and Uncoated Zinc Oxide Nanoparticles: Stability Assessment and Penetration Evaluation by Reflectance Confocal Laser Microscopy

September 2023

The new skin cream with zinc oxide nanoparticles is stable, spreads well, and doesn't deeply penetrate the skin.

research 130 Examples of Tumors Diagnosis Via Quantum Resonance Spectrometer

1 citations , January 2001

Cancer patients have lower immunity and higher virus and zinc levels in their hair.

research Netherton Syndrome With Trichorrhexis Invaginata “Bamboo Hair” Under Dermoscopy: Case Images

December 2025 in “Clinical Case Reports”

Netherton syndrome causes skin and hair issues, confirmed by "bamboo hair" under dermoscopy, with no cure but managed with topical treatments.

Panax Notoginseng Saponins Promote Hair Follicle Growth in Mice via Wnt/Beta-Catenin Signaling Pathway

research Panax notoginseng saponins promote hair follicle growth in mice via Wnt/β‐Catenin signaling pathway

March 2023 in “Chemical biology & drug design”

Panax notoginseng saponins help hair growth in mice.

research ENHANCEMENT OF FINASTERIDE AQUEOUS SOLUBILITY BY NANOSUSPENSION OPTIMIZATION DESIGN

November 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

Nanosuspension increased finasteride's water solubility by over 2.5 times.

Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite

research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite

16 citations , October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology”

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

research S.04.04 Social isolation alters GABAA receptors plasticity and function: effect of ethanol

October 2007 in “European Neuropsychopharmacology”

research Multiple layers structured polyvinyl alcohol/titanium dioxide@polydopamine/ZIF-8 composite fibers and their minoxidil-loaded composites

January 2026 in “SSRN Electronic Journal”

Synthesis and Biological Evaluation of 4-(4-(Alkyl- and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-Steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2

research Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2

8 citations , March 2002 in “Archiv Der Pharmazie”

The compound 4c effectively inhibits the enzyme linked to hair loss.

research The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin

14 citations , July 2015 in “International Journal of Molecular Sciences”

S-Methylmethionine sulfonium can protect skin from UVB damage.

research Signaling and Gene Expression for Water-Tolerant Legume Nodulation

22 citations , August 2006 in “Critical Reviews in Plant Sciences”

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.