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Did you mean Discoid Lupus Erythematosus?

GlossaryDiscoid Lupus Erythematosus

chronic autoimmune condition causing red, scaly skin patches

Discoid Lupus Erythematosus (DLE) is a chronic autoimmune condition that primarily affects the skin, leading to the development of red, inflamed, and scaly patches, often on the face, scalp, and ears. These lesions can cause scarring and permanent hair loss if they occur on the scalp.

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Research

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research Trichoscopic Features of Scalp Discoid Lupus Erythematosus versus Lichen Planopilaris: A Systematic Review

4 citations , April 2024 in “Clinical Cosmetic and Investigational Dermatology”

Trichoscopy helps distinguish between scalp Discoid Lupus Erythematosus and Lichen Planopilaris for accurate diagnosis and treatment.

Clinical and Trichoscopic Features of Scalp Discoid Lupus Erythematosus in Skin of Color: A Retrospective Analysis

research Clinical and trichoscopic features of scalp discoid lupus erythematosus in skin of colour: A retrospective analysis

June 2026 in “Indian Journal of Dermatology Venereology and Leprology”

Scalp discoid lupus erythematosus shows two distinct patterns in skin of color.

research Pediatric Discoid Lupus Erythematosus with Scalp-Exclusive Involvement: Trichoscopy and Response to Early Minipulse Corticosteroid Therapy

June 2025 in “Scholars Journal of Medical Case Reports”

Early minipulse corticosteroid therapy can effectively treat scalp discoid lupus in children.

research Isolated Linear Discoid Lupus Erythematosus of Scalp Following Lines of Blaschko

2 citations , December 2019 in “The Open Dermatology Journal”

Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.

research Dramatic Response of Scarring Scalp Discoid Lupus Erythematosus (DLE) to Intravenous Methylprednisolone, Oral Corticosteroids, and Hydroxychloroquine in a 5-Year-Old Child

19 citations , May 2009 in “Pediatric Dermatology”

A 5-year-old girl's scalp scarring and hair loss from lupus improved with specific medications.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

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Experts

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Trichologist
Kirsten J. Scalp
Greenville, SC, United States

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Kirsten J. Scalp