3 citations
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May 2016 in “Dermatopathology” Lrig1 could be a marker for advanced sebaceous carcinoma.
16 citations
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July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
34 citations
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February 2012 in “American Journal of Dermatopathology” Calretinin can help identify certain skin structures and tumors.
14 citations
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January 2015 in “Hormones and Cancer” The study explored the role of androgen receptors (AR) in skin cancer susceptibility in mice, revealing that AR inactivation delayed the onset of skin cancers in both genders when exposed to systemic DMBA treatment, while also reducing cumulative cancer incidence compared to wild-type mice. Male mice were more susceptible to carcinogen-induced skin cancer than females, indicating gender differences in susceptibility. However, in a two-stage carcinogenesis model with local DMBA/TPA treatment, AR inactivation increased papilloma numbers, suggesting different tumorigenesis mechanisms between systemic and local treatments. AR inactivation also altered skin structure and Cox-1 and Cox-2 expression, indicating a molecular mechanism for AR's effect on skin cancer susceptibility, with gender differences persisting even in AR knockout mice.
2 citations
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January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.