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GlossarySebaceous Gland

small skin gland producing oily sebum for lubrication

A sebaceous gland, also known as an oil gland, is a small gland in the skin that produces sebum, an oily substance that helps to lubricate and protect the skin and hair. These glands are typically found in high concentrations on the face and scalp and are connected to hair follicles, releasing sebum through the hair follicle to the surface of the skin.

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community possible treatment of AGA and change in sebaceous gland condition and oil production using sulfur soap

in Research/Science 4 upvotes 9 months ago

Sulfur soap may help with hair thickening and reducing scalp inflammation, but it can cause dryness. Nizoral, containing ketoconazole, is noted for its potential to reduce seborrheic dermatitis but may also cause scalp dryness and hair loss.

community Hot weather causing hair shedding?

in Minoxidil 3 upvotes 7 months ago

Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.

community Why does Finasteride make my hair not get greasy fast anymore?

in Finasteride/Dutasteride 31 upvotes 2 years ago

Finasteride, a hair loss treatment, was observed to reduce scalp oiliness in users. Anti-androgens like Finasteride are known to decrease the activity of oil-producing glands.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Anyone on Dutasteride have reduced scalp oil?

in Finasteride/Dutasteride 13 upvotes 1 year ago

Dutasteride may reduce scalp oil and itchiness more effectively than finasteride, with some users experiencing drier skin and improved hair thickness. Users report varying results, with some noticing benefits after switching from finasteride to dutasteride, while others use a combination of treatments including minoxidil.

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Research

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research Inactivation of autophagy leads to changes in sebaceous gland morphology and function

27 citations , July 2018 in “Experimental dermatology”

Autophagy is crucial for normal sebaceous gland function and sebum composition.

research Growth of the Mouse Coat VII. Hair Cycles and Sebaceous Glands in Homozygous and Heterozygous Naked Mice

2 citations , January 1960 in “Australian Journal of Biological Sciences”

The Naked gene in mice causes abnormal sebaceous glands and disrupts hair follicle organization.

research Sebaceous Gland Regeneration in Human Skin Xenografts

9 citations , May 2010 in “Journal of Investigative Dermatology”

Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.

An Updated Review of the Sebaceous Gland and Its Role in Health and Diseases Part 1: Embryology, Evolution, Structure, and Function of Sebaceous Glands

research An updated review of the sebaceous gland and its role in health and diseases Part 1: Embryology, evolution, structure, and function of sebaceous glands

13 citations , December 2020 in “Dermatologic Therapy”

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

research 574 Murine sebaceous gland homeostasis requires intact cutaneous innervation in a hair cycle-dependent context

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

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