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GlossarySerum IgE Levels

concentration of antibodies in blood related to allergies

Serum IgE Levels refer to the concentration of Immunoglobulin E (IgE) antibodies in the blood. These antibodies are part of the immune system and are typically elevated in allergic reactions and certain parasitic infections. Measuring IgE levels can help diagnose and monitor conditions like asthma, eczema, and other allergic disorders.

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Research

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Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level

research Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level

24 citations , January 2012 in “Indian Journal of Dermatology, Venereology and Leprology”

Diffuse alopecia areata involves more inflammation and higher allergy-related antibodies than patchy types.

research Correlation between increased total serum IgE levels and clinical features in alopecia areata patients

1 citations , June 2025 in “Frontiers in Immunology”

Higher IgE levels may play a role in alopecia areata, especially in males, children, and severe cases.

research Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28‐Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels

10 citations , December 2024 in “Allergy”

Tralokinumab effectively improved atopic dermatitis symptoms in most patients, but some stopped due to side effects like hair loss.

Expanding The Phenotype Of Hyper-IgE Syndrome: Heterozygous Variant In IL6ST With Elevated Serum IgE And Isolated Abscesses

research P378: Expanding the phenotype of hyper-IgE syndrome: Heterozygous VUS in IL6ST with elevated serum IgE and isolated abscesses

January 2024 in “Genetics in Medicine Open”

A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.

research Lanceolate hair-J (lah^J ): A mouse model for human hair disorders

37 citations , June 2000 in “Experimental dermatology”

The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.

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