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research Short sequence repeats of the intergenic spacer regions of ribosomal RNA genes in Malassezia globosa and M. restricta colonizing the scalps of male individuals with and without androgenetic alopecia

April 2022 in “Microbiology and Immunology”

A specific DNA pattern in Malassezia restricta may be linked to hair loss in men.

research 16．微生物学研究室

July 2023 in “Institutional Repositories DataBase (IRDB)”

Malassezia species may contribute to hair loss in AGA patients.

Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus

research Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus

3 citations , January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia

research Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia

60 citations , January 2007 in “Human Genetics”

AR polyglycine repeat doesn't cause baldness.

research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice

January 2016 in “Human & Experimental Toxicology”

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

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Community Join

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community What happened to the big three? Ketoconazole is pretty magic for some and over the last few years it has been missing in people’s regiment quite a bit

in Product 109 upvotes 1 year ago

Ketoconazole, once popular for hair health, is now less mentioned, with mixed reviews on its benefits for scalp health. Microneedling is discussed as a potential alternative to traditional treatments like finasteride and minoxidil, with varied opinions on its effectiveness.

community End of Hair loss ( AGA ) ? Since they produce it in china probably we don’t need to wait other 10 yrs😁

in Treatment 274 upvotes 4 months ago

GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 5 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 4 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.

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Experts

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Hair System Specialist
Hayley Short
Plymouth, United Kingdom

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Hayley Short