Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
A 24-year-old switched from finasteride to dutasteride and increased oral minoxidil from 5 mg to 7.5 mg, noticing increased hairshedding. Users discuss the safety and effects of high-dose minoxidil, with some suggesting the shedding may be temporary due to dosage changes.
Hair loss in men is primarily caused by androgenetic alopecia, with treatments like finasteride and dutasteride often recommended. Other causes include stress, nutritional deficiencies, medications, and scalp infections.
The user is experiencing diffuse hair loss despite using finasteride and dutasteride and is considering adding minoxidil, microneedling, or RU58841. They are also thinking about increasing the dutasteride dose or opting for a hair transplant, while being cautious about side effects.
A user's two-year hair regrowth journey using 0.5 mg Dutasteride, 5mg oral Minoxidil, 0.75ml of 8% RU58841, and Nizoral shampoo a few times a week. Other users suggest adding microneedling and topical Minoxidil for better results.